OBJECTIVES To assess the relative effect of different types of stimuli on agitated behaviors of nursing home residents with dementia. DESIGN Repeated-measures design with randomized assignment of conditions. SETTING Seven Maryland nursing homes. PARTICIPANTS One hundred eleven nursing home residents with a diagnosis of dementia who exhibited agitation. INTERVENTION Different types of st...

Despite the value that osteopathic manipulative medicine (OMM) may offer to healthcare consumers in a managed care, evidence-based healthcare system, very little research has been published on the cost-effectiveness of osteopathic manipulative treatment compared with other treatment modalities. The authors searched MEDLINE and OSTMED for English-language articles published between January 1966 ...

Several parasite species are known to manipulate the phenotype of their hosts in ways that enhance their own transmission. Co-occurrence of manipulative parasites, belonging to the same species or to more than one species, in a single host has been regularly observed. Little is known, however, on interactions between co-occurring manipulative parasites with same or different transmission routes...

BACKGROUND Dysfunction of the cervicothoracic spine and the adjacent ribs (also called the shoulder girdle) is considered to predict occurrence and poor outcome of shoulder symptoms. It can be treated with manipulative therapy, but scientific evidence for the effectiveness of such therapy is lacking. OBJECTIVE To study the effectiveness of manipulative therapy for the shoulder girdle in addit...

Educational research has demonstrated that the use of concrete objects or manipulatives in the classroom enhances problem-solving skills and conceptual learning. This project examines the use of manipulatives in a neurophysiology curriculum and assesses their effectiveness on student comprehension. Three activities, building an ion channel, building a nerve cell, and passive membrane properties...

This paper presents a study of the use of a digital manipulative developed to promote creative narrative construction and storytelling. The study was carried with 27 groups of preschoolers, of five years of age, who interacted with the digital manipulative during free-play time, during a period of six months. The study sought to access aspects of children’s embodiment of the narratives, and how...

Ecologists have used a variety of comparative mensurative and manipulative experimental approaches to study the biological consequences of habitat fragmentation. In this paper, we evaluate the merits of the two major approaches and offer guidelines for selecting a design. Manipulative experiments rigorously assess fragmentation effects by comparing preand post-treatment conditions. Yet they are...