Formative, also called asymmetric, cell divisions produce daughter cells with different identities. Like other divisions, formative divisions rely first of all on the cell cycle machinery with centrally acting cyclin-dependent kinases (CDKs) and their cyclin partners to control progression through the cell cycle. However, it is still largely obscure how developmental cues are translated at the ...

Studies in non-human primates and humans reveal that discrete regions (henceforth, "divisions") in the basal ganglia are intricately interconnected with regions in the cerebral cortex. However, divisions within basal ganglia nuclei (e.g., within the caudate) are difficult to identify using structural MRI. Resting-state functional connectivity MRI (rs-fcMRI) can be used to identify putative cere...

Stem cells and neuroblasts derived from mouse embryos undergo repeated asymmetric cell divisions, generating neural lineage trees similar to those of invertebrates. In Drosophila, unequal distribution of Numb protein during mitosis produces asymmetric cell divisions and consequently diverse neural cell fates. We investigated whether a mouse homologue m-numb had a similar role during mouse corti...

Text mining is one of Artificial Intelligent (AI) technologies that uses Natural Language Processing (NLP) for extracting data from structured text. Sentiment analysis (also known as opinion mining) text techniques, which the computational study personals' behaviours and opinions. The importance sentiment increases extensively with enormous growth internet sites such e-commerce, blogs, social m...

We consider a setting in which a single divisible good (“cake”) needs to be divided between n players, each with a possibly different valuation function over pieces of the cake. For this setting, we address the problem of finding divisions that maximize the utilitarian social welfare, focusing on divisions where each player needs to get one contiguous piece of the cake. We provide a constant fa...

Immediately following fertilisation in Drosophila and many other arthropods, the embryo undergoes a series of rapid syncytial nuclear divisions. These divisions are driven by maternally supplied components and occur in the absence of zygotic transcription. Unlike typical cell divisions, these divisions alternate between S and M phases, resulting in cell cycles that last only from 10 to 25 min. ...