The aim of the present study was to assess the profiles of the exoglycosidases: N-acetyl-β-hexosoaminidase, β glucuronidase and β galactosidase, α mannosidase and α fucosidase in fibroblast culture undergoing replicative and stress-induced senescence. Half of the cell culture was grown in normal conditions, without the stressor, and the other half of the cell was treated with 0.15 mM tert-butyl...

Modification of Airway Smooth Muscle Responses in the Guinea Pig by Hydrocortisone, in Vitro and in Vivo. Ca& Es BRINK, PAMELA RIDGWAY AND JAMES S. DOUGLAS 1 Mechanism of Isoproterenol-Induced Desensitization of Tracheal Smooth Muscle. CHIH-SHION LIN, LEON HURWITZ, JOHN JENNE AND B .iuty P. AVNER 12 Inactivation of Norepinephrine in an Isolated Vein. FERNANDO Bit NDAo 23 Histamine Mediation in ...

α1-Antitrypsin is a serine protease inhibitor produced in the liver that is responsible for the regulation of pulmonary inflammation. The commonest pathogenic gene mutation yields Z-α1-antitrypsin, which has a propensity to self-associate forming polymers that become trapped in inclusions of endoplasmic reticulum (ER). It is unclear whether these inclusions are connected to the main ER network ...

in this research genetic and phenotypic parameters were estimated using linear and threshold models, for reproductive traits, data from 6 large industrial dairy herd of east azerbaijan province collected by agriculture jihad organization during 10 years (2001-2010). best linear unbiased predictions of traits breeding values were estimated using restricted maximum likelihood method by wombat sof...

objective: this study was conducted to investigate the effectiveness of education based of the cognitive, metacognitive, and behavioral model on the reduction of meta-worry beliefs in patients with social anxiety disorder (sad). methods: the research was a quasi-experimental study with pretest-posttest design and a control group. the statistical population comprised all patients with sad referr...

control of sedimentation in dam reservoirs is considered to be one of the most important issues in exploitation of dams and increasing the their useful life. reservoirs act as traps for sediments and prevent transport of sediment to the river. the deposited sediment decreases the capacity of reservoirs so that they can not be in use any more. various methods dealing with removing part of the de...

middle east is a strategic region because of its abundant oil reserves, hostile struggles among the countries, and threat of the radical groups. the countries of this region spend a large amount of their annual budgets on buying weapons and war armaments. the purpose of this paper is to study the impact of military expenditures on economic growth of oil and non-oil middle east countries by a dy...

BACKGROUND In this study we have investigated the effects of type I (insulin-dependent) and II (non-insulin dependent) diabetes mellitus on the specific activity and the output of salivary exoglycosidases: N-acetyl-β-hexosoaminidase (HEX), and its isoenzymes A and B (HEX A, HEX B), and β-glucuronidase (GLU) in well controlled diabetic patients compared to healthy age-matched controls. MATERIA...

AIM Colorectal cancer is characterized by high morbidity and mortality in developed countries. The lack of low-cost, easy-to-use screening diagnostic methods is one of the causes of late diagnosis of colorectal cancer. Beta-glucuronidase (GLU) is a lysosomal exoglycosidase involved in degradation of glycosaminoglycans of the cell membranes and extracellular matrix of normal and cancerous colon ...