نتایج جستجو برای: marker validation
تعداد نتایج: 301287 فیلتر نتایج به سال:
PURPOSE The high risk of recurrence after transurethral resection of bladder tumor of nonmuscle invasive disease requires lifelong treatment and surveillance. Changes in DNA methylation are chemically stable, occur early during tumorigenesis, and can be quantified in bladder tumors and in cells shed into the urine. Some urine markers have been used to help detect bladder tumors; however, their ...
PURPOSE To evaluate plasma cystatin level as a covariate to predict topotecan pharmacokinetics. Cystatin C, a member of the cystatin superfamily of cysteine proteinase inhibitors, has been recently proposed as an alternative endogenous marker of glomerular filtration. Renal function is known as a key factor of topotecan clearance. EXPERIMENTAL DESIGN Data were obtained from 59 patients who un...
The present study aimed to assess impact of selection based on microsatellite-genotypes at ADL0176 and the association MCW0044 located chromosome number-2 with growth layer economic traits in RIR chicken could reveal when sire component influenced progeny-birds different genotypes microsatellites. DD, EE CC/AD-genotypes microsatellite had corresponding higher BW28, BW40 EW40 progeny than other ...
Standards for the development of therapeutically relevant biomarkers and biomarker based classification systems are lacking. The literature of prognostic marker studies for breast cancer is inconsistent and few such markers have been adopted for widespread use in clinical practice. This is problematic as many patients are overtreated and many others are treated ineffectively. The deficiencies i...
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