In the formation of long-term memories, a "spaced" distribution of study sessions is more beneficial than closely spaced "massed" study sessions. Pagani et al. (2009) examine the molecular basis of this spacing effect in Drosophila and find a role for the SHP2 homolog, corkscrew, an activator of Ras/MAPK signaling, in establishing optimal spacing intervals.

Background and Purpose Deficits in upper-extremity function in individuals with tetraplegia are primarily due to the loss of motor pathways. Detrimental cortical reorganization, however, may create further loss of function. The purpose of this case report is to describe the cortical changes associated with a combination intervention using bimanual massed practice training with somatosensory sti...

Here we tested whether the well-known superiority of spaced training over massed training is equally evident in both object identity and object location recognition memory. We trained animals with objects placed in a variable or in a fixed location to produce a location-independent object identity memory or a location-dependent object representation. The training consisted of 5 trials that occu...

INTRODUCTION Clinical research highlights the importance of massed practice in the rehabilitation of chronic post-stroke aphasia. However, while necessary, massed practice may not be sufficient for ensuring progress in speech-language therapy. Motivated by recent advances in neuroscience, it has been claimed that using language as a tool for communication and social interaction leads to synergi...

BACKGROUND Implementation intentions are mental representations of simple plans to translate goal intentions into behavior under specific conditions. Studies show implementation intentions can produce moderate to large improvements in behavioral goal achievement. Human associative memory mechanisms have been implicated in the processes by which implementation intentions produce effects. On the ...

BACKGROUND The left midfusiform and adjacent regions have been implicated in processing and memorizing familiar words, yet its role in memorizing novel characters has not been well understood. METHODOLOGY/PRINCIPAL FINDINGS Using functional MRI, the present study examined the hypothesis that the left midfusiform is also involved in memorizing novel characters and spaced learning could enhance...

This paper describes NETtalk, a class of massively-parallel network systems that learn to convert English text to speech. The memory representations for pronunciations are learned by practice and are shared among many processing units. The performance of NETtalk has some similarities with observed human performance. (i) The learning follows a power law. (ii) The more words the network learns, t...

The practice conditions within dance training have remained essentially unchanged for decades. Those conditions appear to be based largely on a “culture of rigor,” a philosophy of which implies that continuous practice is the most beneficial way to improve (motor) skills. Current evidence in motor learning supports the concept of “distributed practice,” in which the resting phase within a pract...

Repetition has long been known to facilitate memory performance, but its effects on event-related potentials (ERPs), measured as an index of recognition memory, are less well characterized. In Experiment 1, effects of both massed and distributed repetition on old-new ERPs were assessed during an immediate recognition test that followed incidental encoding of natural scenes that also varied in e...