نتایج جستجو برای: matrine
تعداد نتایج: 404 فیلتر نتایج به سال:
Journal:
:Molecules
2017
Yiming Xu
Lichuan Wu
Hang Dai
Mingyan Gao
Haroon Ur Rashid
Haodong Wang
Peng Xie
Xu Liu
Jun Jiang
Lisheng Wang
Using sophoridine 1 and chalcone 3 as the lead compounds, a series of novel α, β-unsaturated sophoridinic derivatives were designed, synthesized, and evaluated for their in vitro cytotoxicity. Structure-activity relationship (SAR) analysis indicated that introduction of α, β-unsaturated ketone moiety and heterocyclic group might significantly enhance anticancer activity. Among the compounds, 2f...
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