OBJECTIVE To investigate the metabolic response of skeletal muscle to exercise in patients with chronic heart failure and determine its relation to central haemodynamic variables. SETTING University hospital in Sweden. PARTICIPANTS 16 patients in New York Heart Association class II-III and 10 healthy controls. MAIN OUTCOME MEASURES Skeletal muscle biopsies were obtained from the quadricep...

BACKGROUND increasing age affects aerobic capacity, with an average loss of 10% or more per decade. AIM to determine the effect of ageing on the circulatory system in middle-aged men during 33 years of physical training. METHODS 15 men initially aged 45 years took part in an exercise training programme for 25-33 years. Nine serial measurements were made at rest and during maximal effort. Ae...

Maximal oxygen intake and other associated physiological variables were measured during strenuous exercise on fairly active women subjects (N = 20, physical education majors). The method described by Taylor et al. (14) was essentially used. Following assessment of maximal oxygen intake, all subjects underwent an all-out performance test at the work level which had elicited her maximal oxygen in...

To study the effects of positional restraint on heart rate and oxygen saturation during recovery, a crossover experimental design with prospective control trials was used in a two-phase study. In phase 1, serial resting oxygen saturations (RO1) measured on 18 volunteers were compared with those measured in the seated unrestrained (SU1) and the hogtie (HT) positions after submaximal cycle exerci...

PURPOSE The 6 minutes walk test (6MWT) is often shown to be the best predictor of mortality in pulmonary hypertension (PH) probably because it challenges the failing heart to deliver adequate cardiac output. We hypothesised that the 6MWT elicits maximal cardiac output as measured during a maximal cardiopulmonary exercise testing (CPET). METHODS 18 patients with chronic thromboembolic pulmonar...

Scott C, Wyatt F, Winchester J, Williamson K, Welter A, Brown S. Physiological Breakpoints and Maximal Steady-State of Cycling. JEPonline 2015;18(3):33-45. The aim of this study was to examine various physiological thresholds and their association with maximal steady-state exercise. Elite level cyclists (n = 15) participated in the study. All data were collected on a Velotron cycle ergometer, l...