BACKGROUND Patients with early-stage lung cancer who have a high baseline lymphocyte-to-monocyte ratio (LMR) have a favorable prognosis. However, the prognostic significance of LMR in patients with advanced-stage EGFR-mutant non-small cell lung cancer (NSCLC) receiving first-line epidermal growth factor receptor (EGFR)-tyrosine kinase inhibitors (TKIs) has not been established. We conducted a r...

The aim of this work is to evaluate the influence of cyclophosphamide and its principal metabolites (CPs) on microbial behaviour in a membrane bioreactor system. Two laboratory-scale membrane bioreactors (MBR) were run in parallel with a sludge retention time of 70 days (one with the cytostatic drugs, MBR-CPs, the second without, MBR-control). The microbial activity was measured by respirometri...

This paper uses calibrated versions of a sticky-price currency-substitution model to compare the initial dynamics and welfare costs of three types of stabilization program: Ž . Ž . exchange-rate-based ERB , money-based MB , and money-based with initial reliqueficaŽ . tion MBR . ERB and MBR programs are found to induce an initial expansion in real activity, whereas MB programs are initially cont...

This study investigated the effects of salinity increase on bacterial community structure in a membrane bioreactor (MBR) for wastewater treatment. The influent salt loading was increased gradually to simulate salinity build-up in the bioreactor during the operation of a high retention-membrane bioreactor (HR-MBR). Bacterial community diversity and structure were analyzed using 454 pyrosequencin...

Minimum Bayes Risk (MBR) has been used as a decision rule for both singlesystem decoding and system combination in machine translation. For system combination, we argue that common MBR implementations are actually not correct, since probabilities in the hypothesis space cannot be reliably estimated. These implementations achieve the effect of consensus decoding (which may be beneficial in its o...

With the rural-to-urban population migration under new era of rapid urbanization, China has experienced dramatic rural land change, especially change in cultivated and residential land, resulting serious uncoordinated human–land relationships areas. The efficient use these two kinds resources becomes one paramount challenges for governments to achieve sustainable balanced development. This chal...

INTRODUCTION Sinus node dysfunction (SND) commonly manifests with atrial arrhythmias alternating with sinus pauses and sinus bradycardia. The underlying process is thought to be because of atrial fibrosis. We assessed the value of atrial fibrosis, quantified using late gadolinium enhanced-MRI (LGE-MRI), in predicting significant SND requiring pacemaker implant. METHODS Three hundred forty-fou...

PURPOSE The purpose of this study was to evaluate the correlation between laser speckle flowgraphy measurements of mean blur rate (MBR) and hydrogen gas clearance measurements of capillary blood flow (CBF) in the optic nerve head (ONH) of albino and pigmented rabbits, with or without chronic ischemia-induced ONH atrophy. METHODS The ONH MBR and ONH CBF were measured at baseline, 30 and 60 min...

This study focuses on the application of combining membrane bioreactor (MBR) treatment with reverse osmosis (RO) or nanofiltration (NF) membrane treatment for removal of pharmaceuticals and personal care products (PPCPs) in municipal wastewater. Twenty-seven PPCPs were measured in real influent with lowest average concentration being trimethoprim (7.12 ng/L) and the highest being caffeine (18.4...

The bracing components in steel I-girder bridge systems are essential structural for the bridges to restrain their rotation due lateral torsional buckling (LTB). Current design specifications require be installed prevent sections from unexpectedly twisting instability. To estimate internal forces acting on elements, we can use approximate equations that provide considerably conservative values....