We present a simple formalism that has proven useful in on-axis alignment of two-element telescopes when wavefront information is available from only a limited region (here two noncontiguous subapertures) of the pupil. Misalignments cause predictable full-aperture aberrations, which in turn cause predictable tip/tilt modes in the subapertures. For the most useful case in which secondary mirror ...

Mechanical alignment with conventional total knee arthroplasty (TKA) instruments often requires collateral ligament releases, which result in a high prevalence of adduction and reverse axial rotation (external rotation) of the tibial component during knee flexion with a variety of component designs. We used a radiographic image-matching technique to determine the contact kinematics during stand...

Our study evaluated the accuracy of an image-guided total knee replacement system based on CT with regard to preparation of the femoral and tibial bone using nine limbs from five cadavers. The accuracy was assessed by direct measurement using an extramedullary alignment rod without radiographs. The mean angular errors of the femur and tibia, which represent angular gaps from the real mechanical...

Modern total knee arthroplasty is effective at treating the pain and disability associated with osteoarthritis. The number of total knee replacements done in the USA continues to increase. Despite the great care taken during all of these procedures, some patients remain dissatisfied with their outcome. While this dissatisfaction is likely multifactorial, malalignment of the prosthetic component...

Mesenchymal stem cells (MSCs) have been cited as contributors to heart repair through cardiogenic differentiation and multiple cellular interactions, including the paracrine effect, cell fusion, and mechanical and electrical couplings. Due to heart-muscle complexity, progress in the development of knowledge concerning the role of MSCs in cardiac repair is heavily based on MSC-cardiomyocyte cocu...

Collagen is the most abundant extracellular-network-forming protein in animal biology and is important in both natural and artificial tissues, where it serves as a material of great mechanical versatility. This versatility arises from its almost unique ability to remodel under applied loads into anisotropic and inhomogeneous structures. To explore the origins of this property, we develop a set ...

BACKGROUND Few studies have compared the effect of different computer navigation systems on postoperative alignment in patients who have had total knee arthroplasty (TKA). We examined 2 computed tomography (CT)-free computer navigation systems by comparing the accuracy of intraoperative measurements to postoperative alignment. METHODS Patients underwent unilateral TKA performed by a single su...

The alignment uncertainties of the CMS Tracker detector, made of a huge amount of independent silicon sensors with an excellent position resolution, affect the performances of the track reconstruction, the track parameters measurement and the vertex reconstruction. In order to study the impact of the mis-alignment of the CMS tracking devices on the previous procedures, realistic estimates for t...