introduction : root-end preparation and restoration with an endodontic material are required when nonsurgical endodontic retreatment has failed or is impossible. the present clinical study reports the treatment outcomes of periradicular surgery using calcium-enriched mixture (cem) cement. materials and methods: a prospective outcome study of periradicular surgery using cem was conducted on 14 p...

background: human dental stem cells have high proliferative potential for self-renewal that is important to the regenerative capacity of the tissue. objective: the aim was to isolate human dental pulp stem cells (dpsc), periodontal ligament stem cells (pdlsc) and periapical follicle stem cells (pafsc) for their potential role in tissue regeneration. materials and methods: in this experimental s...

introduction: during the last decade, advances in tissue engineering and stem cell-based tooth regeneration have provided realistic and attractive means of replacing lost or damaged teeth. the first adult stem cells isolated from dental tissues were dental pulp stem cells (dpscs). when transplanted with hydroxyl apatite/tri calcium phosphate (ha/tcp) powder, they formed a dentin-like structure ...

Avulsion injury is one of the most severe types traumatic dental injuries. Following avulsion, periodontal ligament tissues are injured and vessels nerves pulp rupture at apical foramen which causes necrosis. In studies it was reported that key to retention knocked-out teeth maintain viability ligament. Storage media plays an important role in preserving PDL cells during extra alveolar time. Th...

OBJECTIVE To investigate the effect of low-frequency mechanical vibration (LFMV) on the prevention of relapse after active orthodontic tooth movement, bone volume fraction (BVF), tissue density, and the integrity of periodontal ligament. MATERIALS AND METHODS Thirty male CD1, 12-week-old mice were used for the study. Mice were randomly divided into three groups: 1. control group, 2. relapse g...

Brain-derived neurotrophic factor (BDNF), for which bovine collagen-derived atelocollagen is used as a scaffold, enhances periodontal tissue regeneration. However, a scaffold that does not contain unknown ingredients is preferable. Since the synthesized high-molecular-weight (HMW)-hyaluronic acid (HA) is safe and inexpensive, we evaluated the efficacy of HMW-HA as a BDNF scaffold. CD44, a major...

Abstract Purpose The quantitative percussion diagnostics (QPD) response of a mandibular second molar and maxillary central incisor including their supporting ligament/bone structure was simulated using dynamic 3D finite element analysis (FEA). focus the work on role periodontal ligament (PDL) which acts as damper in dental dissipates occlusal forces transmitted from tooth surface to surrounding...

Objective- Investigating of the isolation, culture, differentiation potential and electronic microscopic characterization of canine periodontal ligament stem cells (PDLSCs). Design- Experimental in vitro study Animals- Four intact, male, mongrel dogs, 8-10 months-old were selected to collect PDLSCs from their teeth. Procedures- The dogs were anesthetized and the first maxillary and mandibula...

Periodontal ligament cells (PDLCs), which have potential for multilineage differentiation, are candidates for use in regeneration of periodontal tissue defects; however, our understanding of the mechanisms underlying the lineage commitment of PDLCs remains limited. C4orf7, which is specifically expressed in the periodontal ligament (PDL) tissue, may be crucial in deciding the fate of PDLCs and ...