A new limonoid, belonging to the havanensin-type, called pentandricine E (1), alongside four other known types, i.e., trichilenone acetate (2), toonaciliatones C (3), 11α-acetoxyazadirone (4) and ceramicine I (5), were found in Chisocheton pentandrus stem bark. The structures of isolated 1-5 identified by NMR spectroscopy HRTOFMS. Pentandricine (1) displayed highest cytotoxicity toward MCF-7 br...