The aim of the present study was to evaluate the antioxidant effects of aqueous fruit extract of Ziziphusjujuba on ethanol-induced oxidative stress and to examine its protective effects on sperm motility and plasma membrane integrity of male Wistar rats. Adult male rats (n = 28) were divided into four equal groups: the first group served as untreated controls, the second group of rats was given...

Myricetin (3, 5, 7-Trihydroxy -2(3, 4, 5-trihydroxyphenyl) 4-chromenone), a naturally occurring flavonol, is a potent scavenger of reactive oxygen species (ROS) and effectively prevent erythrocyte oxidation. The protective effect of myricetin on proteins and lipids of erythrocytes membranes was investigated. Erythrocytes membranes were subjected to oxidative stress by incubating them with 10 M ...

Cytoprotective properties of potassium channel openers (KCOs) have been demonstrated in several models of cell injury, mainly in ischemia-reperfusion-induced damage of cardiac muscle. The mechanism responsible for the observed cytoprotection and the relative contribution of plasma membrane or inner mitochondrial membrane potassium channels regarding the beneficial effects exerted by KCOs remain...

High incidence of multiple kidney stone formation has been observed among workers exposed to cadmium (Cd). Citrate is known to be a protective factor against renal stone formation. To study the direct effect of cadmium on citrate uptake by the renal brush border membrane, we exposed isolated rat renal brush border membrane vesicles (BBMV) to cadmium and determined their citrate uptake character...

PURPOSE Recently, we reported finding that circulating melatonin levels in age-related macular degeneration patients were significantly lower than those in age-matched controls. The purpose of this study was to investigate the hypothesis that melatonin deficiency may play a role in the oxidative damage of the retinal pigment epithelium (RPE) by testing the protective effect of melatonin and its...

The effect of ethanol on the cytoplasmic membrane of Oenococcus oeni cells and the role of membrane changes in the acquired tolerance to ethanol were investigated. Membrane tolerance to ethanol was defined as the resistance to ethanol-induced leakage of preloaded carboxyfluorescein (cF) from cells. To probe the fluidity of the cytoplasmic membrane, intact cells were labeled with doxyl-stearic a...

extractdefective corneas are the leading cause of blindness world wide and the second leading cause, after diabetic retinopathy,of blindness in the united state , afflicting 30000 americans each year. happily, nearly 95 percent of those who have corneal transplantations( in 1985 they numbered,26300) regain their sight. the cornea is a transparent, a vascular, dim-sized tissue continious with th...