How does FGF (fibroblast growth factor) signaling induce both neural and mesodermal cell fates in the early embryo? Two papers address this fundamental question in this issue of Cell. Bertrand et al. show in the ascidian that a GATA factor determines the neural response of animal cells to FGF signaling, while in the chick, Sheng et al. demonstrate that the slow induction by FGF of a new transcr...

Sarcomatoid squamous cell carcinomas are extremely rare, high grade, aggressive variant of penile cancers. Sarcomatoid carcinoma are biphasic neoplasms with a combination of both sarcomatoid components and carcinomatous elements. These neoplasms are very rare in the urogenital system. We report a 53-year-old male presented with an ulcerated lesion on the glans penis. The rarity of this case rei...