Cadmium (Cd) is a toxic heavy metal with no known biological function in plants and one of the most substances released into environment. Crops, such as rice, maize, wheat tobacco are major sources Cd for humans. toxicity inhibits crop growth development by affecting many central physiological biochemical processes, finally it affects human health via food chain. To adapt to toxicity, crops hav...

The metabolic resistance of plants to herbicides is similar the herbicide metabolism process accelerated by safeners. tolerance fenoxaprop-P-ethyl (FE) distinct among different varieties rice in which phytotoxicity forms easily, resulting restricted use FE paddy. Safener effectively resolves this issue. This study showed that 9311 and Meixiangzhan No. 2 (MXZ) had mechanisms FE. Isoxadifen-ethyl...

conclusions adherence to the meddiet, according to mds and sofi-mds, may not predict mets components and mets incidence after 3 years of follow-up in iranian adult populations. results after adjusting for potential confounders, neither higher mds nor higher sofi-mds were significantly associated with the mean values of mets components and the risk of metabolic abnormalities incidence after 3 ye...

Plants are frequently exposed to natural and synthetic toxins such as heavy metals, allelochemicals, organic pollutants, and pesticides. Consequently, plants must mount specific and coordinated defense mechanisms for survival under adverse growing conditions (Zhang et al., 2007). One such mechanism is the capability for metabolizing organic compounds from abiotic origin (xenobiotics). Extensive...

Thioredoxin reductase (TrxR) is an enzyme that involved in many metabolic pathways from detoxification to reduction of radicals by catalyzing the thioredoxin, and therefore associated with physiological processes, including cancer. Inhibitors this are considered anticancer targets. In past studies, some antidepressants have been found effects through various mechanisms, reuse as drugs has attra...

Rationally designed nanoparticles that can bind toxins show great promise for detoxification. However, the conventional intravenous administration of nanoparticles for detoxification often leads to nanoparticle accumulation in the liver, posing a risk of secondary poisoning especially in liver-failure patients. Here we present a liver-inspired three-dimensional (3D) detoxification device. This ...

Nitrosodiethylamine (NDEA) is a potent carcinogen widely existing in the environment. Our previous study has demonstrated that garlic oil (GO) could prevent NDEA-induced hepatocarcinogenesis in rats, but the underlying mechanisms are not fully understood. It has been well documented that the metabolic activation may play important roles in NDEA-induced hepatocarcinogenesis. Therefore, we design...