Metabolic syndrome (MS) is a widespread polyethiological clustering characterized by metabolic, hormonal disorders and clinical manifestations that significantly increase the risk of developing cardiovascular diseases, atherosclerosis, type II diabetes other pathological conditions. An important role in development MS assigned to intestinal microbiota. To develop new therapeutic agents for corr...

Adipose tissue (AT) acts as a highly active endocrine organ, which secretes wide range of adipokine hormones. In the past few years, several adipokines (leptin, adiponectin, resistin etc.) have been discovered showing metabolic consequences in relation to insulin resistance (IR), obesity and diabetes. These are considered be an important component playing role regulation energy metabolism. They...

Objective: Mild hypoandrogenism in men is associated with features of the metabolic syndrome, but the association with the metabolic syndrome itself using an accepted definition has not been described. Design: Men with the metabolic syndrome were identified and testosterone and sex hormone-binding globulin (SHBG) levels were determined in a population-based cohort of 1896 non-diabetic middleage...

The satiating effects of cow dairy have been thoroughly investigated; however, the effects of goat dairy on appetite have not been reported so far. Our study investigates the satiating effect of two breakfasts based on goat or cow dairy and their association with appetite related hormones and metabolic profile. Healthy adults consumed two breakfasts based on goat (G-Breakfast) or cow (C-Breakfa...

Metabolic hormones affect ovarian function in the cow. However, the relationship between metabolic factors and ovarian function is not clear in the postpartum primiparous cow because they are still growing. The aim of the present study was to investigate in detail the time-dependent profile of the metabolic hormones, metabolites, and milk yields of ovulatory and anovulatory primiparous cows dur...

Background & aimsHuman milk is the gold standard for infant nutrition. Preterm infants whose mothers are unable to provide sufficient own mother's (OMM), receive pasteurized donor human (DHM). We studied metabolic signatures of OMM and DHM their effect on interplay developing microbiota infant's metabolism.MethodsMetabolic fingerprinting as well urine was performed using liquid chromatography–m...

Background. It has been shown before that drinking mineral waters of different composition a significant effect on the neuroendocrine, metabolic and immune parameters healthy rats. We analyzed canonical correlations between neuroendocrine parameters, one hand, other hand. Materials Methods. Experiment was performed 58 female Wistar rats 240-290 g. HRV major adaptation hormones, metabolism immun...