نتایج جستجو برای: metanephrines
تعداد نتایج: 296 فیلتر نتایج به سال:
Recently, we reported an LC-MS/MS method for measuring Pmets using ion-pairing solid phase extraction (IP-SPE) and porous graphitic carbon (PGC) column chromatography1, 2. Although the method is fast and analytically sensitive, it can be further improved by automating the offline sample preparation with online sample preparation technology, which is more timeand cost-effective. Thermo Scientifi...
Pheochromocytomas (PCCs) are rare neuroendocrine tumors. The current diagnostic tools are based on biochemistry and histopathology results, but heterogeneity of diagnostic markers, signs and symptoms of PCCs bring a lot of difficulties for these two current methods. Unfortunately microscopic understanding of PCCs is not adequate for its confident prognosis and management. There are data linking...
CONTEXT Measurements of plasma methoxytyramine, the O-methylated dopamine metabolite, are useful for detecting rare dopamine-producing pheochromocytomas and paragangliomas (PPGLs) and head and neck paragangliomas (HNPGLs), but utility for screening beyond that achieved using standard measurements of normetanephrine and metanephrine is unclear. OBJECTIVE Evaluation of the additional utility of...
We describe a case of a 25-year-old female with a dopamine secreting PPGL diagnosed retrospectively with biochemical analysis. This finding resulted in change in approach to investigation and management, given their important clinical implications. There are important differences in management of dopamine secreting PPGL compared to classical noradrenaline and adrenaline-secreting PPGL. This inc...
Hilden lists some of these limitations in his letter; another important one is its global interpretation, which does not translate well into clinical practice (1 ). The partial area under the ROC curve in the clinically relevant range of false-positive rates, or falsenegative rates, is a useful alternative measure of inherent diagnostic accuracy. Dr. Hilden advocates performance measures that i...
نمودار تعداد نتایج جستجو در هر سال
با کلیک روی نمودار نتایج را به سال انتشار فیلتر کنید