objective: therapeutic interventions can be classified into two distinct approaches: abstinent and maintenance method. currently, there are no clear criteria for referring addicted patients to one of these modalities. we aimed to compare the personality characteristics of individuals with addiction who attended narcotics anonymous sessions with those who received methadone maintenance therapy. ...

This pilot study simultaneously evaluated the effects of various factors, including genetic variations of CYP2B6, CYP2C19, and ABCB1, demographic characteristics, disease states, methadone-drug interactions (MDIs), and poly-substance use, on the treatment responses among non-HIV patients in the methadone maintenance treatment program (MMTP) in Taiwan. A total of 178 patients were recruited from...

Maintenance therapy with methadone or buprenorphine is an established and first-line treatment for opioid dependence. Clinical studies indicate that about a third of patients in opioid maintenance therapy show increased alcohol consumption and alcohol use disorders. Comorbid alcohol use disorders have been identified as a risk factor for clinical outcome and can cause poor physical and mental h...

We examine the impact of transfers between methadone treatment prescribing physicians on 1-year retention. Episode data (n=13,359; 1996 to 2001) drawn from a Canadian population-based methadone registry were analysed using a binary logistic regression model. The odds ratios for remaining in treatment for 365 days or more decreased for repeated episodes of treatment, but increased with age and n...

Opiates have provided relief from psychic and physical pain for millennia, but their abuse and control has created an international scourge of addiction, misery, crime, and disease. Furthermore, because opiates are frequently administered intravenously, abusers may suffer from and transmit infections, including HIV, hepatitis B, and hepatitis C. Methadone maintenance remains the most successful...

BACKGROUND In France, methadone has historically been less accessible than buprenorphine. In 2008, a dry formulation (capsule) was introduced into the market, aimed in particular to improve methadone accessibility. OBJECTIVE To describe the impact (prevalence of use, patient profiles and compliance with requirements) of the dry methadone formulation in France. METHOD A retrospective cohort ...

Background: Borderline Personality disorder is a disabling disease affecting 2% of general population. Various drugs have been suggested for treatment of borderline Personality disorder. If a drug could alleviate a wide range of symptoms, it would be more suitable. In these disorders drug addiction is very common. This fact makes the symptoms complicated and the treatment more difficult. This...

Abstract Background: Socio-behavioral consulting centers offer methadone maintenance therapy which is a very useful method for drug dependents. These centers offer a wide range of services like education, consulting, prevention, care taking of patients and treatment for high risk groups such as AIDS-infected patients. Methadone maintenance therapy (MMT) is helpful in harm minimization...

Substance abuse is also related to psychological skills that affect the treatment process. Identifying the role of these skills can be useful for the development of a better intervention. This purpose of this study was to compare the coping strategies and emotion regulation profiles among opium users, methadone maintenance treatment clients, and normal individuals. The sample was selected among...

BACKGROUND AND AIMS For HIV-positive individuals who use illicit opioids, engagement in methadone maintenance therapy (MMT) can contribute to improved HIV treatment outcomes. However, to our knowledge, the role of methadone dosing in adherence to antiretroviral therapy (ART) has not yet been investigated. We sought to examine the relationship between methadone dose and ART adherence among a coh...