نتایج جستجو برای: methoxychlor

تعداد نتایج: 270  

Journal: :Toxicological sciences : an official journal of the Society of Toxicology 2006
Daniel A Symonds Kimberly P Miller Dragana Tomic Jodi A Flaws

Although the ovarian surface epithelium (OSE) is responsive to hormones and endocrine-disrupting chemicals, little information is available on the metabolizing capabilities of the OSE. Thus, we tested the hypothesis that the OSE is capable of expressing genes regulating phase I metabolism of estrogen and the estrogenic endocrine disruptor methoxychlor (MXC). To test this hypothesis, we isolated...

2014
Bingbing Chen Dongxin Chen Zheli Jiang Jingyang Li Shiwen Liu Yaoyao Dong Wenwen Yao Benson Akingbemi Renshan Ge Xiaokun Li

The objective of the present study is to determine whether methoxychlor (MXC) exposure in adulthood affects rat Leydig cell regeneration and to compare its effects with estradiol (E2). Adult 90-day-old male Sprague-Dawley rats received ethane dimethane sulfonate (EDS) to eliminate the adult Leydig cell population. Subsequently, rats were randomly assigned to four groups and gavaged with corn oi...

Journal: :Toxicological sciences : an official journal of the Society of Toxicology 2006
Xiao-Juan Wang Erika Bartolucci-Page Suzanne E Fenton Li You

Genistein (GE) is a prevalent phytoestrogen whose presence in human and animal foods may affect biological actions of synthetic endocrine active compounds. We have previously reported that in utero and lactational exposure to high doses of GE or the endocrine active pesticide methoxychlor (MXC) caused mammary epithelial proliferation in 21-day-old male rats. Combined exposure to GE and MXC resu...

2015
Sandra Regina Rissato Mário Sergio Galhiane João Roberto Fernandes Marli Gerenutti Homero Marques Gomes Renata Ribeiro Marcos Vinícius de Almeida

Phytoremediation is an attractive alternative to conventional treatments of soil due to advantages such as low cost, large application areas, and the possibility of in situ treatment. This study presents the assessment of phytoremediation processes conducted under controlled experimental conditions to evaluate the ability of Ricinus communis L., tropical plant species, to promote the degradatio...

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