Sonochemical procedure was used to synthesize Co/β-cyclodextrin complex. For the first time, Fe/β-cyclodextrin complex also synthesized in alkaline media. Moreover, β-cyclodextrin modified by citric acid (CA) and reacted with metal salts under ultrasonic irradiation. The prepared catalysts were characterized using EDX, UV–vis FTIR analytical techniques. highest incorporation of into observed cr...

Cyclodextrins, even the 6-membered α-cyclodextrin, are approved in the various pharmacopoeias as pharmaceutical excipients for solubilizing and stabilizing drugs as well as for controlling drug release. Recently α-cyclodextrin has also been marketed as health food with beneficial effects on blood lipid profiles. However, the concentration of α-cyclodextrin used may be very high in these cases, ...

The unusual self-assembly in chloroform of a novel cyclodextrin-based [2]pseudorotaxane, composed of heptakis-2,6-di-O-methyl-3-O-acetyl-β-cyclodextrin and a viologen-containing linear component, is reported.

Soft attachment of streptavidin to β-cyclodextrin-modified pegylated SAMs was efficiently performed in a reversible and repetitive way via orthogonal bifunctional linkers involving streptavidin-biotin recognition and redox-driven multivalent host-guest (β-cyclodextrin-ferrocene) interactions.

Amphiphilic cyclodextrins have been synthesized with self-acylating reaction using vinyl esters in dimethylformamide. In the present study no base, catalyst, or enzyme was used, and the structural analyses using thin layer chromatography, nuclear magnetic resonance spectroscopy and mass spectrometry show that the cyclodextrin is substituted preferentially by one acyl moiety at the C2 position o...

The aim of this in vivo study was to assess the ability of the prodrug conjugate diclofenac-β-cyclodextrin to release diclofenac in the colon following oral administration, using sulfapyridine (a metabolite of sulfasalazine) as a marker of colonic absorption. Two groups of rats were used; the test rats received a suspension containing the two prodrugs, diclofenac-β-cyclodextrin and sulfasalazin...

A mono-6-O-propargyl permethylated beta-cyclodextrin, 3, has been prepared by two synthetic routes as a versatile building block for the construction of cyclodextrin dimers and trimers with a core junction which is potentially electron conducting. Glaser-Hay coupling of 3 gave beta-cyclodextrin dimer 6, and Pd(0)-catalysed coupling allowed the preparation of a cyclodextrin dimer with a 1,4-phen...

Cyclodextrin glucanotransferase (CGTase, EC 2.4.1.19) is an important member of α-amylase family which can degrade the starch and produce cyclodextrins (CDs) as a result of intramolecular transglycosylation (cyclization). β-Cyclodextrin production was carried out using the purified CGTase enzyme from an alkaliphile Microbacterium terrae KNR 9 with different starches in raw as well as gelatinize...

The inclusion behavior of hydroxypropyl β-cyclodextrin and natural β-cyclodextrin was studied toward ketoprofen, in order to develop a new oral dosage form with enhanced dissolution rate and bioavailability, and to study the oral pharmacokinetics of ketoprofen in humans, following cyclodextrin complexation. Drug-cyclodextrin solid systems were prepared by kneading, co-evaporation, and freeze-dr...