Primary hyperparathyroidism is caused by a single parathyroid adenoma in the majority of patients. Localization of parathyroid adenomas prior to surgery has the benefit of allowing a minimally invasive approach. Over the years, multiple imaging modalities have been employed in an attempt to identify the site preoperatively, with varying degrees of success. In this study, we explore the accuracy...

OBJECTIVE To correlate myocardial perfusion scintigraphy (MPS) with Tc-99m-MIBI and adenosine infusion using quantitative coronary angiography (QCA) and intravascular ultrasound (IVUS). METHODS Seventy patients with coronary artery disease (CAD) referred for myocardial perfusion scintigraphy (MPS) with MIBI and adenosine were studied. Clinical, electrocardiographic (ECG), and scintigraphic fi...

OBJECTIVE To determine the usefulness of parathyroid hormone (PTH) measurement in needle aspirates of a suspicious neck mass to confirm its parathyroid nature in patients with primary hyperparathyroidism. METHODS Thirty-three patients with surgically proved primary hyperparathyroidism were submitted to neck ultrasound (US), parathyroid scintigraphy, and assay of PTH in the aspirate (PTHa) of ...

BACKGROUND We aimed to evaluate the diagnostic performance of 99mTc-MIBI SPECT/CT and ultrasonography in patients with secondary hyperparathyroidism (SHPT), and explored the factors that affect the diagnostic performance. METHODS 99mTc-MIBI SPECT/CT and ultrasonography were performed in 50 patients with SHPT within 1 month before they underwent surgery. Imaging results were confirmed by the p...

Hypercalcemia is a rare but serious metabolic condition that may lead to end-organ damage. Primary hyperparathyroidism disease in children and adolescents parathyroid adenoma the most common cause. Most of patients are clinically symptomatic present signs or symptoms hypercalcemia. The aim this report describe two case hypercalcemia due presenting with different clinical findings. 14 years old ...

The sestamibi scan (MIBI) and ultrasound (US) are used for preoperative localization of parathyroid adenoma (PTA), with sensitivity as high as 90%. We developed 4-dimensional magnetic resonance imaging (4D MRI) as a novel tool for identifying PTAs. Eleven patients with PTA were enrolled. 4D MRI from the mandible to the aortic arch was used. Optimization of the timing of image acquisition was ob...

UNLABELLED Parathyroid cystic adenomas are often misdiagnosed as thyroid cysts and routine preoperative diagnostic tools, such as ultrasonography (US) or 99m technetium-sestamibi (99mTc-MIBI) scans, cannot clearly distinguish between these entities. We present a 67-year-old hypercalcemic woman with a cervical cystic lesion who had negative sestamibi scan results. Her laboratory data indicated p...

1St. Louis, Missouri; 2Northwestern University, Chicago, Illinois; 3Thomas Jefferson University, Philadelphia, Pennsylvania; 4Southern Molecular Imaging, Savannah, Georgia; 5St. Thomas’ Hospital, London, United Kingdom; 6North Shore–Long Island Jewish Health System, New Hyde Park, New York; 7Barnes–Jewish Hospital, St. Louis, Missouri; 8Vanderbilt University, Nashville, Tennessee; and 9Milton S...