Addresses: *Department of Pathology, Stanford University, Stanford, CA 94305, USA. †Department of Biochemistry, Stanford University, Stanford, CA 94305, USA. ‡Department of Genetics, Stanford University, Stanford, CA 94305, USA. § Howard Hughes Medical Institute, Stanford University, Stanford, CA 94305, USA. ¶Current address: Lewis-Sigler Institute for Integrative Genomics, Princeton University...

Abstract New technology such as DNA microarray can be used to determine simultaneously the expression levels of the thousands of genes which determine the function of all cells. Applying this technology to investigate the gene-level responses to different drug treatments could provide deep insight into the nature of many diseases as well as lead in the development of new drugs. In this paper, w...