Digital microfluidic systems (DMFS) are a class of lab-on-a-chip systems that manipulate individual droplets of chemicals on an array of electrodes. The biochemical analyses are performed by repeatedly moving, mixing, and splitting droplets on the electrodes. In this paper, we characterize the tree structure of biochemical analyses and identify their minimum resource requirements, towards the d...

Microfluidic technology is the emerging technologies in researching fluid channel and related applications in the micro and nano-scale space. Microfluidic chip is a new miniaturized rapid analysis platform by microfluidic technology, it has many characteristics such as liquid flow control, minimal reagent consumption, rapid analysis, which is widely used in physics, chemistry, biology, and engi...

Intellectual property rights are essential in today's technology-driven age. A strong intellectual property protection strategy is crucial in the bioinformatics and biochips technology spaces as monetary and temporal resources are tremendous in finding a blockbuster drug or gene therapy, as well as in deploying advanced biosensor and other medical systems. Current problems and intellectual prop...

This paper presents a review of microtechnologies relevant to applications in cellular physiology, including biochips, electrochemical sensors and optrodic sensing techniques. Microelectrodes have been the main tools for measuring cellular electrophysiology, oxygen, nitric oxide, neurotransmitters, pH and various ions. Optical fiber sensing methods, such as indicator-based optrodes, with fluore...

Microfluidic technology plays an essential role in various lab on a chip devices due to its desired advantages. An automated microfluidic system integrated with actuators and sensors can further achieve better controllability. A number of microfluidic actuation schemes have been well developed. In contrast, most of the existing sensing methods still heavily rely on optical observations and exte...

3.1 Definition...........................................................................................2 3.2 Short Description..................................................................................2 3.3 State of R&D .......................................................................................2 3.3.1 Nanophase Materials ........................................................

This paper presents novel handheld analyzer with disposable lab-on-chips for electrical detection of anesthetic propofol in human serum samples for clinical diagnostics. The developed on-chip biosensors are based on molecularly imprinted conducting polymer techniques. In this paper, we have designed, fabricated, and characterized the developed system with disposable lab-on-chips for detection o...

Matrix-assisted laser desorption/ionization time-of-flight mass spectrometry (MALDI-TOF-MS) analysis of immuno-captured target protein efficiently complements conventional immunoassays by offering rich molecular information such as protein isoforms or modifications. Direct immobilization of antibodies on MALDI solid support enables both target enrichment and MS analysis on the same plate, allow...