This article explores possible mechanisms governing extracellular matrix deposition in engineered cartilaginous cell pellets. A theoretical investigation is carried out alongside an experimental study measuring proteoglycan and collagen volume fractions within murine chondrogenic (ATDC-5) cell pellets. The simple mathematical model, which adopts a nutrient-dependent proteoglycan production rate...

We aimed to elucidate the role of the Ca-independent PKC isoenzyme PKCdelta in the regulation of spontaneous in vitro chondrogenesis occurring in a 6-day-long culturing period in chicken limb bud-derived high density cell cultures (HDC). PKCdelta expression and activity were detectable throughout the entire culturing period with a peak on days 2 and 3, when most of the chondroblasts differentia...

We have previously demonstrated that elevation of free cytosolic Ca(2+) concentration at the time of differentiation of chondroblasts was mainly due to a Ca(2+) influx and it was indispensable to cartilage formation in chicken high density mesenchymal cell cultures (HDC) [C. Matta, J. Fodor, Z. Szijgyarto, T. Juhasz, P. Gergely, L. Csernoch, R. Zakany, Cytosolic free Ca(2+) concentration exhibi...

Carolina Coli Zuliani, Mariana Freschi Bombini, Kleber Cursino de Andrade, Ronei Mamoni, Ana Helena Pereira, Ibsen Bellini Coimbra* Reumatologia, Clinica Medica, Universidade Estadual de Campinas, Campinas, SP, BR. Tocoginecologia, Universidade Estadual de Campinas, Campinas, SP, BR. III Imunologia, Patologia Clinica, Universidade Estadual de Campinas, Campinas, SP, BR. IV Laboratorio Nacional ...

in this article, regarding threefold nature of iranian culture (iranian, islamic, western) and using descriptive- analytic method, it is investigated about ideas of  shariati, soroush amd rajai on iranian culture to use in fusional approach. shariati emphasized on recognizing awareness of islam with passion and action, the efficiency conscious from west instead of blind imitation, knowing tradi...

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