Introduction . The high mortality rate in patients with lung cancer (LC) is due to the lack of highly sensitive diagnostic markers this disease. Genetic and epigenetic alterations tumor cells, for example, aberrant microRNA expression, can be proposed. It known that extracellular/circulating biological fluids, complexes proteins, or packaged extracellular vesicles interest diagnosis diseases. A...

Epithelial plasticity involved the terminal and transitional stages that occur during epithelial-to-mesenchymal transition (EMT) mesenchymal-to-epithelial (MET), both are essential at different of early embryonic development have been co-opted by cancer cells to undergo tumor metastasis. These processes regulated multiple instances, whereas post-transcriptional regulation key genes mediated mic...

Circulating microRNA expression levels can serve as diagnostic/prognostic biomarkers in several types of malignant tumors; however, to our knowledge, there have been reports describing their value in cervical squamous cell carcinoma (SCC). In this study, we used hybridization arrays to compare the microRNA expression profiles in cervical squamous cell carcinomas (SCC) samples among patients wit...