Systemic acquired resistance (SAR) is a salicylic acid (SA)-dependent heightened state of resistance against a broad spectrum of pathogens activated in the uninoculated systemic tissue of a pathogen-infected plant. For systemic protection to be initiated, a mobile signal that is produced at the site of primary infection needs to travel through the plant. Although the mobile signal (s) for SAR h...

Systemic acquired resistance (SAR) is a salicylic acid (SA)-dependent heightened state of resistance against a broad spectrum of pathogens activated in the uninoculated systemic tissue of a pathogen-infected plant. For systemic protection to be initiated, a mobile signal that is produced at the site of primary infection needs to travel through the plant. Although the mobile signal (s) for SAR h...

At each of the well-defined stages of atherosclerosis, Ang II has the potential to contribute to the vascular pathobiology. For example, type 1 atherosclerotic lesions are defined by the presence of increased numbers of macrophages in the vascular intima and by the formation of foam cells.1 At this early stage of atherosclerosis, Ang II facilitates the recruitment of monocytes/macrophages into ...

A recent publication (Smith et al., 2013) reported the genome sequence of the sea lamprey (Petromyzon marinus). This dataset allows the exploration of early vertebrate evolution because the lamprey lineage split from that of other vertebrates before the emergence of hinged jaws, the defining feature of jawed vertebrates (gnathostomata, ranging from sharks to humans). Additionally, lamprey axons...

according to the well-known classification of dyck, inherited peripheral neuropathies can be categorized as hereditary motor and sensory neuropathies (hmsn) or charcot – marie – tooth (cmt) disease, hereditary motor neuropathies (hmn), and hereditary sensory neuropathies (hsn). cmt is a clinically and genetically heterogeneous group of motor and sensory neuropathies, and is the most common inhe...

Osteosarcomas arising from the cortical surface of bone can be subdivided into parosteal, periosteal, and high grade osteosarcomas, with parosteal osteosarcomas being most well differentiated.1Hang J.F. Chen P.C.H.C. Parosteal steosarcoma.Arch Pathol Lab Med. 2014; 138: 694-699Crossref PubMed Scopus (36) Google Scholar Clinically, show female predominance generally occur in third decade life, d...

Accurate protein quantitation in complex mixtures is crucial for obtaining reproducible biological and biochemical data for both upstream and downstream applications. Colorimetric protein assays are frequently used to determine protein concentration; however, the calculated concentration can vary depending on the sample composition, sequence of the protein, and the time point within the chemica...

We report the complete sequence of the microtubule-associated protein MAP1B, deduced from a series of overlapping genomic and cDNA clones. The encoded protein has a predicted molecular mass of 255,534 D and contains two unusual sequences. The first is a highly basic region that includes multiple copies of a short motif of the form KKEE or KKF_~ that are repeated, but not at exact intervals. The...

Primary cultures of mouse brain astrocytes have been used to identify the microtubule-associated proteins (MAPs) present in this cell type at different stages of in vitro differentiation. The MAPs of the astrocyte have been identified by polyacrylamide gel electrophoresis and immunological detection. Two antisera were raised against two brain MAPs, tau and MAP-2. These antisera were also used t...

INTRODUCTION: Bone loss induced by hypoxia is associated with various pathophysiological conditions such as ischemia, vascular diseases, and osteolytic bone metastases, however, little is known about the mechanism of hypoxia-regulated osteogenesis and bone formation. RUNX2 (also known as CBFA1) is a master regulator of skeletogenesis and its expression is required for osteoblast differentiation...