Fetomaternal alloimmune thrombocytopenia (FMAIT) is caused by maternal generation of antibodies specific for paternal platelet antigens and can lead to fetal intracranial hemorrhage. A SNP in the gene encoding integrin beta3 causes a clinically important maternal-paternal antigenic difference; Leu33 generates the human platelet antigen 1a (HPA-1a), whereas Pro33 generates HPA-1b. As a potential...

PURPOSE Anterior temporal lobe resection (ATLR) controls seizures in up to 70% of patients with intractable temporal lobe epilepsy (TLE) but, in the language dominant hemisphere, may impair language function, particularly naming. Functional reorganization can occur within the ipsilateral and contralateral hemispheres. We investigated reorganization of language in left-hemisphere-dominant patien...

Diabatic heating fromdeepmoist convection in the hurricane eyewall produces a towering annular structure of elevated potential vorticity (PV). is structure has been referred to as a hollow PV tower. e sign reversal of the radial gradient of PV satises the Charney-Stern necessary condition for combined barotropic-baroclinic instability. For thin enough annular structures, small perturbations gr...

The goal of this study is to examine the impact assimilating satellite derived surface temperature over land (LST) in scheme AROME-France model. LST retrieved from SEVIRI radiances during assimilation process atmospheric performed using an optimal interpolation technique, similarly other near-surface parameters (temperature and relative humidity at 2 meters). Observation background errors were ...

In video games, pathfinding must be done quickly and accurately. Not much computational time is allowed for pathfinding, but realistic looking paths are required. One approach to pathfinding which attempts to satisfy both of these constraints is to perform pathfinding on abstractions of the map. Botea et al.’s Hierarchical Pathfinding A* (HPA*) does this by dividing the map into square sectors ...

INTRODUCTION The aim of the present study was to determine the brain areas associated with fibromyalgia, and whether pretreatment regional cerebral blood flow (rCBF) can predict response to gabapentin treatment. METHODS A total of 29 women with fibromyalgia and 10 healthy women (without pain) matched for age were finally enrolled in the study. Technetium-99m ethyl cysteinate dimer single phot...

Objective(s): This study aimed to investigate the effect of aerobic training on serum levels of Klotho, cardiac tissue levels of H2O2 and phosphorylation of ERK1/2 and P38 as well as left ventricular internal diameter (LVID), the left ventricle wall thickness (LVWT) and fibrosis in middle-aged rats. Materials and Methods: Forty wistar rats, including young rats (n=10, 4 month-old) and middle-ag...

This study is designed to identify whether circadian rhythms of the hormones of the hypothalamic-pituitary-adrenal (HPA) axis are associated with corresponding circadian fluctuations in cytokines in a rat model of collagen-induced arthritis (CIA). CIA is induced in Wistar rats by an intradermal injection of bovine type II collagen emulsified with complete adjuvant at the left foot. On day 33, i...

the effective patterns and mechanisms of synoptic systems during the wet and dry spells in midwest of iran(mwi) analyzed and discussed on seasonal scales from 1974 to 2003. synoptic analysis is based on synoptic chartson sea level pressure (slp), 850 and 500 hpa levels. the results of synoptic analysis show that dry spells in mwiare mostly corresponded to azores high (azh) intensifying and its ...

BACKGROUND Alloimmunization against human platelet antigens (HPAs) during pregnancy is rare but can lead to severe bleeding disorders, such as fetal and neonatal alloimmune thrombocytopenia. STUDY DESIGN AND METHODS In a cohort of 241 uncomplicated pregnancies, we investigated the immunogenicity of HPA mismatches and correlated HLA sensitization with HPA antibody formation. HPA antibodies wer...