Joel Kupersmith, MD; Henry L. Lew, MD, PhD; Alex K. Ommaya, ScD; Michael S. Jaffee, MD; Walter J. Koroshetz, MD Traumatic brain injury (TBI) is one of the foremost medical problems resulting from the wars in Afghanistan and Iraq. In 2006, 13,969 active-duty servicemen and servicewomen with incident TBI were treated in the military medical system; of those, 7.6 percent were hospitalized [1]. Whi...

The national dialogue on traumatic brain injury has reached significant amplitude with the public platform of professional sports raising awareness, the experiences of soldiers over a decade of war reinforcing the implications, and the medical community rising with innovative efforts to improve diagnosis and care. Of the estimated 3.8 million traumatic brain injuries (TBI) sustained each year i...

BACKGROUND Feedback learning is essential for behavioral development. We investigated feedback learning in relation to behavior problems after pediatric traumatic brain injury (TBI). METHOD Children aged 6-13 years diagnosed with TBI (n = 112; 1.7 years post-injury) were compared with children with traumatic control (TC) injury (n = 52). TBI severity was defined as mild TBI without risk facto...

BACKGROUND Records of the Rochester Epidemiological Project were used to determine the incidence of secondary seizures after traumatic brain injury (TBI) in all cases treated for this condition in the population of Olmsted County, Minn, from 1935 to 1984. Medical records of the Mayo Clinic and all other medical facilities in Olmsted County, Minn, are in the database of this Project. Incidence r...

OBJECTIVE Following traumatic brain injury, disruption of blood-brain-barrier and consequent brain edema are critical events which might lead to increasing intracranial pressure (ICP), and nerve damage. The current study assessed the effects of aqueous date fruit extract (ADFE) on the aforementioned parameters. MATERIALS AND METHODS In this experimental study, diffused traumatic brain injury ...

traumatic brain injury (tbi) is one of the major causes of severe disability and death in the entire world that accidents are mentioned as main factors of it. tbi lead to primary and secondary injuries.  primary injuries are created immediately after accidents or bleeding but the secondary injuries are created by complicated process of cellular and molecular responses following primary injury a...

Approximately 3.2-5.3 million Americans live with the consequences of a traumatic brain injury (TBI), making TBI one of the most common causes of disability in the world. Visual deficits often accompany TBI but physiological and anatomical evidence for injury in mild TBI is lacking. Axons traversing the corpus callosum are particularly vulnerable to TBI. Hemifield representations of early visua...

Objective(s): Neuroprotective effects of female gonadal steroids are mediated through several pathways involving multiple peptides and receptors after traumatic brain injury (TBI). Two of these peptides are including the regulatory peptides neuromedin U (NMU) and neuromedin S (NMS), and their common receptor neuromedin U2 receptor (NMUR2). This study investigates the effects of physiological do...

177 S everal clinical situations can occur following traumatic brain injury (TBI) depending on the degree and type of brain injury. 1 Being a neurosurgeon and clinician we all aware that patients with traumatic brain injury can have dis abilities represented by motor and sensory impair ments. 2 Several complications that can lead to physical, cog nitive and neurobehavioral disorders can be seen...

There is scattered but significant psychological and neuropsychological evidence to suggest that mild traumatic brain injury (mild TBI) plays a notable role in the emergence and expression of anxiety. Conversely, there is also empirical evidence to indicate that anxiety may exert a pronounced impact on the prognosis and course of recovery of an individual who has sustained a mild TBI. Although ...