Background & Aim:During recent decades, infections disease resulting from opportunistic fungi such as Candida albicans and resistance increasing of human pathogenic bacteria to current antibiotics has led to many problems for treating of these diseases. The aims of the present study was to investigate anti-fungi and anti-bacterial effects of Eucalyptus extract...

objectives: oral infections and dental caries are still considered as serious public health problems and inflict a costly burden to health care services around the world and especially in developing countries. materials and methods: in the present study, we evaluated the antibacterial activity of glycyrrhiza glabra (g. glabra) against oral pathogens by diffusion methods and determined the minim...

The aim of this study was to optimize the dose regimens of enrofloxacin to reduce the development of fluoroquinolone resistance in Escherichia coli (E.coli) using pharmacokinetic/pharmacodynamic (PK/PD) modeling approach. The single dose (2.5 mg/kg body weight) of enrofloxacin was administered intramuscularly (IM) to the healthy pigs. Using cannulation, the pharmacokinetic properties, including...

The inhibitory and bactericidal effects of gentamicin, amikacin, netilmicin (Sch 20569), and carbenicillin were tested against 55 clinical isolates of Serratia marcescens that had been subtyped into 26 strains by biotyping and serotyping. Three major patterns of resistance to gentamicin, netilmicin, and carbenicillin were recognized among these isolates. (i) Most of the 27 isolates that were su...

BACKGROUND Brucellosis is an infectious disease that is caused by Brucella spp. As Brucella spp. are intramacrophage pathogens, the treatment of this infection is very difficult. On the other hand, due to the side effects of the brucellosis treatment regime, it is necessary to find new antimicrobial agents against it. OBJECTIVES The aim of this study was to investigate the antimicrobial effec...

The aim of the present study was to evaluate the antimicrobial activity of Tinospora cordifolia extracts against three standard ATCC strains of Escherichia coli, Staphylococcus aureus and Pseudomonas aeruginosa. The efficacy of extract was measured in terms of Minimum Inhibitory Concentration (MIC), Minimum Bactericidal Concentration (MBC) and zone of inhibition (mm). Antimicrobial activity of ...

conclusions extracts of u. dioica showed significant antibacterial effect against some clinically important pathogenic bacteria. based on the obtained results it can be concluded that u. dioica is useful as antibacterial and bactericidal agent in treating infectious diseases. materials and methods hydroalcoholic extracts from aerial parts were prepared using aqueous solution of ethanol and meth...

BACKGROUND The indiscriminate use of antibiotics in the treatment of infectious diseases can increase the development of antibiotic resistance. Therefore, there is a big demand for new sources of antimicrobial agents and alternative treatments for reduction of antibiotic dosage required to decrease the associated side effects. OBJECTIVES In this study, the synergistic action of aminoglycoside...