Relational database systems are used in thousands of applications every day, including online web shops, electronic medical records and for mobile telephone tracking. Many of these applications have high availability requirements, allowing the database system to be offline for only a few minutes each year. In existing DBMSs, user transactions get blocked during creation of materialized views (M...

Despite advances in the pathophysiology of chronic obstructive pulmonary disease (COPD), there is a distinct lack biochemical markers to aid clinical management. Microvesicles (MVs) have been implicated inflammatory diseases including COPD, but their association COPD severity remains unknown. We analyzed different MV populations plasma and bronchoalveolar lavage fluid (BALF) taken from 62 patie...

Tissue-nonspecific alkaline phosphatase (TNSALP) and Ca-ATPase are known to play roles in bone mineralization, but how these enzymes contribute to appositional mineralization has been illusive. Here we examined the active sites of these enzymes in appositional mineralization using the bones of young rats being administered with 1-hydroxyethylidene-1,1-bisphosphonate (HEBP) for 5 days. The doses...

The present study assesses the diversity and composition of sediment bacterial and microeukaryotic communities from deep-sea mud volcanoes (MVs) associated with strike-slip faults in the South-West Iberian Margin (SWIM). We used a 16S/18S rRNA gene based pyrosequencing approach to characterize and correlate the sediment bacterial and microeukaryotic communities from MVs with differing gas seep ...

Gram-negative bacteria ubiquitously release membrane vesicles (MVs) into the extracellular milieu. Although MVs are the product of growing bacteria, not of cell lysis or death, the regulatory mechanisms underlying MV formation remained unknown. We have found that MV biogenesis is provoked by the induction of PagC, a Salmonella-specific protein whose expression is activated by conditions that mi...

In this review the roles of specific proteins during the first step of mineralization and nucleation are discussed. Mineralization is initiated inside the extracellular organelles-matrix vesicles (MVs). MVs, containing relatively high concentrations of Ca2+ and inorganic phosphate (Pi), create an optimal environment to induce the formation of hydroxyapatite (HA). Special attention is given to t...

Poly-methyl methacrylate bone cements contain methyl methacrylate (MMA), which is known for its sensitizing and toxic properties. Therefore, in most European countries and in the USA, guidelines or regulations exist for occupational exposures. The use of vacuum mixing systems can significantly reduce airborne MMA concentrations during bone setting. Our goal was to test two commonly used vacuum ...

background : the application of ventilation systems in industries and workplaces is with the aim of improving environmental conditions for employees. the lack of appropriate ventilation system components design and control methods result in the production of sound and vibration in most components. the purpose of this study was to determine the role of the pad isolator in controlling vibration a...