نتایج جستجو برای: mmc model
تعداد نتایج: 2106802 فیلتر نتایج به سال:
Mashhad Metamorphic Complex (MMC) with metamorphic, granitic intrusions and ophiolite units is situated in the suture zone of Paleotethys in NE Iran. Triassic staurolite-garnet schist of Khalaj represents the highest grade of metamorphism in MMC. In this study EPMA analyses of garnet and biotite used to determine the maximum temperature for regional metamorphism. The pattern of zoning in garnet...
کامپوزیت پایه فلزی (MMCs) از تقویت کننده های غیر فلزی (به عنوان مثال، سرامیک) در ماتریس های فلزی ساخته شده است که دارای ویژگی هایی همچون سختی، مقاومت در برابر سایش و خستگی مطلوب و وزن نسبتا سبک هستند. یکی از کامپوزیت های فلزی با خواص مکانیکی قابل توجه، کامپوزیت پایه تیتانیوم (Ti-MMC) است که به عنوان جایگزینی برای آلیاژهای پایه نیکل در تعداد زیادی از محصولات و بخش های صنعتی، از جمله صنایع خودرو ...
Axial muscles are innervated by motor neurons of the median motor column (MMC). In contrast to the segmentally restricted motor columns that innervate limb, body wall, and neuronal targets, MMC neurons are generated along the entire length of the spinal cord. We show that the specification of MMC fate involves a dorsoventral signaling program mediated by three Wnt proteins (Wnt4, Wnt5a, and Wnt...
OBJECTIVES This study was designed to assess the dose-response relationship between tissue, blood, vaginal and rectal compartment concentrations of tenofovir (TFV) and tenofovir diphosphate (TFVdp) and ex vivo rectal HIV suppression following oral tenofovir disoproxil fumarate (TDF) and rectal administration of TFV 1% vaginally-formulated gel. DESIGN Phase 1, randomized, two-site (US), double...
چکیده هدف: مقایسه نتایج و عوارض جراحی ترابکولکتومی+ میتومایسین C(MMC) و کارگذاری دریچه احمد (Ahmed) در درمان گلوکوم آفاکی در بیماران 16 ساله یا کوچک‌تر به دنبال جراحی آب‌مروارید مادرزادی. روش پژوهش: در این کارآزمایی بالینی تصادفی، 30 چشم دچار گلوکوم آفاکی از 28 بیمار که در آن‌ها فشار داخل چشمی (IOP) با درمان دارویی (حداقل دو دارای ضد گلوکوم موضعی) تحت کنترل نبودند؛ به طور تصادفی در یکی از ...
INTRODUCTION Tumor necrosis factor-α (TNF-α) is a multifunctional, proinflammatory cytokine that mediates pleiotropic biological functions, especially inflammation and immunoregulation. We hypothesized that blocking TNF-α with a monoclonal antibody would decrease inflammation and subconjunctival scarring in an animal model of experimental filtration surgery. METHODS In a randomized, prospecti...
The aim of this study is to investigate the role of chaperonin-containing t-complex polypeptide 1 beta (CCT2) in the regulation of mouse mesangial cell (mMC) contraction, proliferation, and migration with filamentous/globular-(F/G-) actin ratio under high glucose induction. A low CCT2 mMC model induced by treatment of small interference RNA was established. Groups with and without low CCT2 indu...
Myelomeningocele (MMC) is a congenital disease without genetic abnormalities. Neurological symptoms are irreversibly impaired after birth, and no effective treatment has been reported to date. Only surgical repairs have been reported so far. In this study, we performed antenatal treatment of MMC with an artificial skin using induced pluripotent stem cells (iPSCs) generated from a patient with D...
Chromosome aberrations induced by mitomycin C (MMC) were suppressed by aspirin in a mouse micronucleus test with peripheral blood and bone marrow cells. Aspirin at doses of 0.5, 5, and 50 mg/kg was injected intraperitoneally or per administered orally 0.5, 6, or 24 h after administration of MMC and then peripheral blood and/or bone marrow cells were sampled 48 h after administration of MMC. The...
Disposition characteristics of the macromolecular prodrug of mito mycin C (MM< '), mitomycin C-dextran conjugate (MMC-D), in normal and tumor (VX2 carcinoma)-bearing rabbit thigh muscles were studied using the in situ vascular perfusion technique. Three types of cationic MMC-D (MMC-D.,,) and two types of anionic MMC-D (MMC-D.,,) with different carrier molecular weights were used. After bolus ar...
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