lism. Severe changes in the concentration of uric acid causes several diseases such as gout, hyperuricemia and Lesch–Nyhan syndrome. Therefore, the accurate determination of uric acid in urine samples can be a powerful indicator of diagnosing diseases. Thus, many researchers have focused to develop a simple, sensitive and accurate method for determining uric acid. Various methods have been deve...

The present paper reports electrochemical and UV-VIS spectroscopic studies on the process of electrooxidation of quercetin 3,4'-di-O-β-glucopyranoside (Q 3,4'-diglc) molecule, at glassy carbon electrode surface in 0.1 M sodium acetate – acetic acid buffer in 90 % methanol solution. The process starts at 3'-OH group (ring B), followed by oxidation of 5,7-dihydroxyl group in ring A. As a result o...

fabrication and electrochemical characterization of a sensor for the determination of epinephrine (ep), uric acid (ua) and folic acid (fa) is described. the sensor  was prepared using carbon paste electrode (cpe) modified with 3,4-dihydroxybenzaldehyde-2,4-dinitrophenylhydrazone (ddp) and carbon nanotubes (cnts), which makes the modified electrode highly sensitive for the electrochemical detect...

A biofuel cell is a device for converting chemical energy to electrical energy by a simple way. A high-impact anode is prepared in this research. Here, carboxylated multiwall carbon nanotube (COOH-MWCNT), polydiallyldimethyl ammonium chloride (PDDA) and alcohol dehydrogenase were cast on modified glassy carbon with polymethylene green to construct the bioanode for ...

Direct electrochemistry of glucose oxidase (GOD) was achieved when an ionic liquid/GOD-Polyhydroxy-C60 functional membrane was confined on a glassy carbon electrode (GCE). The cyclic voltammograms (CVs) of the modified GCE showed a pair of redox peaks with a formal potential (E°') of - 329 ± 2 mV. The heterogeneous electron transfer constant (k(s)) was 1.43 s-1. The modified GCE response to glu...

Electrochemical and spectroscopic investigations were performed in order to clarify the mechanism of 4nitrobenzene diazonium reduction on glassy carbon in protic medium. The number and nature of the electron transfer processes were found to be strongly correlated to the electrode surface state. On polished electrode two different reduction peaks were observed. Selective electrolyses realized at...

trans-Resveratrol is often considered as one of the quality standards of red wine, and the development of a sensitive and reliable method for monitoring the trans-resveratrol levels in red wine is an urgent requirement for the quality control. Here, a novel voltammetric approach was described for probing trans-resveratrol using a graphene-modified glassy carbon (GC) electrode. The proposed elec...

An electrochemical sensor based on the electrocatalytic activity of functionalized graphene for sensitive detection of paracetamol is presented. The electrochemical behaviors of paracetamol on graphene-modified glassy carbon electrodes (GCEs) were investigated by cyclic voltammetry and square-wave voltammetry. The results showed that the graphene-modified electrode exhibited excellent electroca...

Altered serum and plasma microRNA (miRNA) expression profiles have been observed in numerous human diseases, with a number of studies describing circulating miRNA biomarkers for cancer diagnosis, prognosis and response to treatment, and recruitment to clinical trials for miRNA-based drug therapy already underway. Electrochemical detection of biomarkers in urine has several significant advantage...