Neuromyelitis optica (NMO) is a rare but severely disabling disease, affecting predominantly the optic nerves and spinal cord. Aquaporin-4 (AQP4 IgG) antibodies have been described as characteristic and pathogenic for the disease. Some NMO cases are AQP4 IgG negative, of which a fraction has antibodies against myelin oligodendrocyte glycoprotein (MOG). We report the pregnancy of a 42 year old E...

We deal with a Yukawa-like long-range modified model of gravity (MOG) which recently allowed to successfully accommodate many astrophysical and cosmological features without resorting to dark matter. On Solar System scales MOG predicts retrograde secular precessions of the planetary longitudes of the perihelia ̟ whose existence has been put on the test here by taking the ratios of the estimated ...

The Multiplayer Online Game (MOG) becomes more popular than any other types of computer games for its collaboration, communication and interaction ability. However, compared with the ordinary human communication, the MOG still has many limitations, especially in communication using facial expressions. Although detailed facial animation has already been achieved in a number of MOGs, players have...

dendritic cells (dcs) play an important role in induction of cellular immune responses. it seems that dcs that reside in different organs may be distinct in their ability to  induce immune responses. this study was done to address the differences between spleen and liver dcs in induction of immune response and/or tolerance. cd11c+  dcs were separated from the liver and spleen of c57bl/6 mice an...

In filtering problems the (posterior) state distribution p(x) is recursively estimated given observations y and state dynamics. For nonlinear observation functions, the state distribution can becomemultimodal. Common Solutions are 1.Unimodal Gaussian filter using linearization of obs. function. 2. “Bank of filters” using multiple independent unimodal filters. We present a variational approach f...

Our lab has demonstrated that encephalitogenic T cells can be effectively anergized by treatment with MHC variant peptides, which are analogues of immunogenic peptides containing an amino acid substitution at an MHC anchor residue. The MHC variant peptide of myelin oligodendrocyte glycoprotein (MOG)(35-55) proves an effective treatment as it does not induce symptoms of experimental autoimmune e...

We extend the mixtures of Gaussians (MOG) model to the projected mixture of Gaussians (PMOG) model. In the PMOG model, we assume that q dimensional input data points z(i) are projected by a q dimensional vector w into 1-D variables u(i). The projected variables u(i) are assumed to follow a 1-D MOG model. In the PMOG model, we maximize the likelihood of observing u(i) to find both the model para...

The cell dynamics associated with induction of peripheral T cell tolerance remain largely undefined. In this study, an in vivo model was adapted to two-photon microscopy imaging, and T cell behavior was analyzed on tolerogen-induced modulation. FcγR-deficient (FcγR(-/-)) mice were unable to resist or alleviate experimental allergic encephalomyelitis when treated with Ig-myelin oligodendrocyte g...

Target detection and tracking is an important problem in the automatic surveillance system. This paper proposes a Combined Gaussian Hidden Markov Model based Kalman Filter (CGHMM-KF) scheme for tracking people in multiple camera sensor network for monitoring and tracking of target (person/vehicle) in secured area. To detect the target under different illumination conditions, HMM with Mixture of...