BACKGROUND Alpha-momorcharin (α-MMC) and momordica anti-HIV protein (MAP30) derived from Momordica charantia L. have been confirmed to possess antitumor and antivirus activities due to their RNA-N-glycosidase activity. However, strong immunogenicity and short plasma half-life limit their clinical application. To solve this problem, the two proteins were modified with (mPEG)(2)-Lys-NHS (20 kDa)....

This was a cross-sectional study aimed at assessing environmental lead exposure and its association with blood lead levels, teeth lead levels and IQ of the inhibitants who live near lead mining in Kanchanaburi Province, Thailand. Two hundred fifteen villagers from 6 villages participated in this study. Exposed and non-exposed villagers were asked to perform IQ tests based on Raven's Standard Pr...

Momordica charantia (MC; commonly known as bitter melon) was fermented with Leuconostoc mesenteroides MKJW, MKSR, and KCTC 3719 (LM), Leuconosoc citreum 3526 (LC), their anti-diabetic, anti-dementia, antioxidant activities were evaluated. The fermentation performed for 24 h at 30 °C, non-fermented MCs (CON1 CON2) included comparison. All produced lactic acids, mannitol, dextran, oligosaccharide...

Momordica charantia, também conhecida como Melão Amargo, de São Caetano é amplamente difundida principalmente em países da Índia, Ásia, África e América do Sul, devido ao seu potencial medicinal. À relatos utilização melão amargo há milhares anos diversos modos antidiabético, antifúngico, antioxidante, anti-helmíntica, contraceptiva no tratamento icterícia, hanseníase entre outros. Neste contex...

Major intrinsic proteins (MIPs) family include the group of also called channel or water channels. Aquaporins facilitate transport and other uncharged small molecules, forming pores in cellular boundaries which help plant growth, development, sometimes adaptation. They usually have six tranSmembrane alpha-helical domains with conserved amino acids residues along hydrophobic hydrophilic regions....