W E HAVE HAD a keen interest in the monoamine oxidase inhibitors (MAOinhibitors) from the time that Cesarman' first reported their benefits in the prophylaxis of angina pectoris. Together with two of my associates, Dr. Robert W. Oblath and Dr. Willard J. Zinn, I have used four of the available MAO-inhibitors-iproniazid, isocarboxazid, beta-phenylisopropylhydrazine, and pivalylbenzhydrazine-in t...

In the title compound, C(12)H(12)N(2)O, the dihedral angle between the planes of the pyridine and phenyl rings plane is 35.94 (12)°. In the crystal structure, centrosymmetrically related mol-ecules are linked by a pair of N-H⋯N hydrogen bonds, forming a dimer with an R(2) (2)(8) ring motif. In addition, there is an intra-molecular N-H⋯O inter-action.

In the title mol-ecule, C6H8N2, the endocyclic angles are in the range 118.43 (9)-122.65 (10)°. The mol-ecular skeleton is planar (r.m.s. deviation = 0.007 Å). One of the two amino H atoms is involved in an N-H⋯N hydrogen bond, forming an inversion dimer, while the other amino H atom participates in N-H⋯π inter-actions between the dimers, forming layers parallel to (100).

W E HAVE HAD a keen interest in the monoamine oxidase inhibitors (MAOinhibitors) from the time that Cesarman' first reported their benefits in the prophylaxis of angina pectoris. Together with two of my associates, Dr. Robert W. Oblath and Dr. Willard J. Zinn, I have used four of the available MAO-inhibitors-iproniazid, isocarboxazid, beta-phenylisopropylhydrazine, and pivalylbenzhydrazine-in t...