Background: Concurrent myelomeningocele in twins is a rare clinical presentation, only reported twice Nigeria. Case Description: We present set of identical female from Both were females that presented at 3 years with low back swelling since birth, associated bisphincteric dysfunction but normal motor and sensory functions the lower extremities. They had repair 2 months after presentation there...

Aplasia cutis congenita (ACC) is defined as complete or partial loss absence of skin at birth and it can occur on any part the body, but most commonly scalp. Single offspring with ACC have been reported in case reports, cases twins are rarely reported. Here, we report two ACC, monozygotic twin boys presented scattered over scalp vertex after birth. All lesions ulcers no hair healed scars, other...

We present monozygotic twin boys with features of Kabuki syndrome. The twins were discordant for cleft palate and coarctation of the aorta. The occurrence of Kabuki syndrome in monozygotic twins has not been previously reported and reinforces the belief that this condition has a genetic basis. Chromosomal analysis on the boys showed a pseudodicentric chromosome 13 with an inactive centromere an...

Rett syndrome (RTT) is a severe, progressive, neurodevelopmental disorder predominantly observed in females, that leads to intellectual disability. Mutations and gross rearrangements in MECP2 account for a large proportion of cases with RTT. We investigated 13 year old, monozygotic twin females with RTT and some noticeable differences in development using a combinatorial approach of sequencing ...

The multiple relationships within kinships of adult monozygotic twins permit incisive analyses to be made of genetic and environmental effects on behavioral traits. Data from families of 65 monozygotic twin pairs yield evidence of genetic variance on the Block Design Test, a nonverbal measure of general intelligence.