نتایج جستجو برای: moving target detector mtd
تعداد نتایج: 550611 فیلتر نتایج به سال:
Abstract The insulin therapy used to treat Diabetes Mellitus (DM) lacks educational tools assist self-care. Thus, we aimed develop and validate an tool for the relationship between glycemic variation adults with type 1 2 DM. study was developed in three stages: i) elaboration of tool; ii) validation content display by a panel judges; iii) pre-test target audience. Ten judges participated second...
With the increasing awareness of privacy protection, Virtual Private Networks (VPNs) are widely used to build a more secure communication tunnel. However, traffic hijacking attack called blind in/on-path has seriously threatened security VPNs. Inspired by Moving Target Defense (MTD), VPN architecture (MVPN) is designed defend against such attacks. MVPN includes multiple nodes encrypt and decryp...
Due to the complexity of attack scenarios in container-based cloud environment and continuous changes state microservices, effectiveness active defense strategies decreases with microservice change. To tackle it, main focus is how establish a comprehensive threat model adaptive deployment strategy. In this study, we present an optimal defensive security framework (OADSF) for deep reinforcement ...
Comparison of neuropathy-inducing effects of eribulin mesylate, paclitaxel, and ixabepilone in mice.
Chemotherapy-induced neurotoxicity is a significant problem associated with successful treatment of many cancers. Tubulin is a well-established target of antineoplastic therapy; however, tubulin-targeting agents, such as paclitaxel and the newer epothilones, induce significant neurotoxicity. Eribulin mesylate, a novel microtubule-targeting analogue of the marine natural product halichondrin B, ...
PURPOSE To assess the safety and tolerability of the small-molecule allosteric MEK inhibitor refametinib combined with sorafenib, in patients with advanced solid malignancies. EXPERIMENTAL DESIGN This phase I dose-escalation study included an expansion phase at the maximum tolerated dose (MTD). Patients received refametinib/sorafenib twice daily for 28 days, from a dose of refametinib 5 mg pl...
A large area (128m) Muon Tracking Detector (MTD), located within the KASCADE experiment, has been built with the aim to identify muons (Eμ >0.8GeV) and their directions in extensive air showers by track measurements under more than 18 r.l. shielding. The orientation of the muon track with respect to the shower axis is expressed in terms of the radialand tangential angles. By means of triangulat...
Many natural phenomena such as snow avalanches, debris flows, or lahars involve gravitational transport and deposition that is largely governed by topography. This paper describes a fast and mass-conserving algorithm to parameterize mass transport and deposition (MTD) over a digital elevation model. The algorithm is an extension to existing flow-routing and terrain parameterization techniques. ...
Improvised explosive devices (IED) pose a very serious threat to civilians and military forces around the world, and new technologies must be developed for the early detection of these objects. Because of the high concentrations of low atomic number material such as nitrogen and hydrogen present in these explosives, x-ray backscattering provides a viable method of collecting information about t...
Phase I trials are increasingly including dose-expansion cohorts after the maximum-tolerated dose (MTD) has been reached to better characterize the toxicity profile or identify early signs of efficacy within a specific disease population. This article provides guidelines on how to monitor safety and re-evaluate the MTD using data obtained from expansion cohorts of phase I protocols. We illustra...
Introduction: Patients with muscle tension dysphonia (MTD) suffer from several physical discomforts in their vocal tract. However, few studies have examined the effects of voice therapy (VT) on the vocal tract discomfort (VTD) in patients with voice disorders. Therefore, the aim of the present study was to investigate the effects of VT on the VTD in patients with MTD. Materi...
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