The molecular rotor 9-(2-Carboxy-2-cyanovinyl)julolidine (CCVJ) exists in two isomers. While the E isomer, which is present absence of light, yields a fluorescent behavior, Z isomer photoproduct with no detectable luminescence. This regenerative behavior utilized for Molecular Tagging Velocimetry (MTV).

Purpose: This study compares the value of 3,4-dihydroxy-6-[F]-fluoro-L-phenylalanine (F-FDOPA) positron emission tomography (PET) and MRI in assessing outcome during antiangiogenic treatment in patients with recurrent high-grade gliomas. Experimental Design: Thirty patients were prospectively studied with F-FDOPA PET scans immediately before, and two and six weeks after start of bevacizumab the...

PURPOSE To implement a statistical framework for assessing the precision of several quantitative MRI metrics sensitive to myelin in the human spinal cord: T1, Magnetization Transfer Ratio (MTR), saturation imposed by an off-resonance pulse (MTsat) and Macromolecular Tissue Volume (MTV). METHODS Thirty-three healthy subjects within two age groups (young, elderly) were scanned at 3T. Among them...

Peripheral CD4 T cells in Vβ5 transgenic (Tg) C57BL/6J mice undergo tolerance to an endogenous superantigen encoded by mouse mammary tumor virus 8 (Mtv-8) by either deletion or T-cell receptor (TCR) revision. Revision is a process by which surface expression of the Vβ5(+) TCR is down-regulated in response to Mtv-8 and recombination activating genes are expressed to drive rearrangement of the en...

BACKGROUND The effects of supplementation with different macronutrients on gastric sensory and motor functions are unclear. OBJECTIVE We aimed to compare the effects of 2 wk of supplementation with different classes of macronutrients on gastric function, satiation, and appetite in healthy and overweight subjects. DESIGN In a parallel-group, double-blind study, 52 (14 men, 38 women) healthy ...

Background: Recently, there are many reports from Japan about methotrexate associated lymphoproliferative disorder (MTX-LPD). We investigating the predictive factor of spontaneous regression (SR) in MTX-LPD. On other hand, FDG-PET/CT is used for diagnosis LPD including malignant lymphoma. In addition, it was reported that imaging biomarkers such as metabolic tumor volume (MTV) and total lesion ...

UNLABELLED The aim of this study was to investigate the value of (18)F-FDG parameters of the primary tumor in predicting occult lymph node metastasis in patients with clinically N0 esophageal squamous cell carcinoma. METHODS The study comprised 143 consecutive patients (mean age ± SD, 63.9 ± 8.6 y; range, 31.8-81.2 y) from May 2003 to January 2010 who had clinically N0 esophageal squamous cel...

OBJECTIVE To compare standardized uptake values (SUV) derived from pre-treatment 18F-fluorodeoxyglucose (FDG) positron emission tomography/computed tomography (PET/CT) imaging and clinical prognostic factors in pediatric patients with Hodgkin lymphoma (HL). METHODS Pre-treatment FDG PET/CT findings of 28 children with HL were evaluated in this retrospective study. Metabolic tumor volume (MTV)...

OBJECTIVE Non-Hodgkin's lymphomas arising from tissues other than primary lymphatic sites are classified as primary extranodal lymphomas (PEL). PELs of the gastrointestinal system (PGISL) originate from the lymphatic tissues within the gastrointestinal tract. The prognostic value of 18F-FDG PET/CT in lymphomas is high in terms of both overall survival (OS) and disease-free survival (DFS). Our a...

DCE-MRI provides information about the perfusion of tumours together with morphological details. Perfusion of tumour could be assessed by dynamic 18FDG PET/CT (dFDG/PET), in addition to metabolic information. This study was planned to compare the semi-quantitative parameters of DCE-MRI) and dFDG/PET in locally advanced breast cancer. Forty patients with LABC underwent DCE-MRI and DFDG/PET study...