The fungus Rhizopus oryzae which belong to the order Mucorales is a unique test agent to study the effects of metabolic alterations on infection since it behaves differently in the metabolically normal and abnormal host. This fungus was originally isolated at autopsy from a diabetic patient who died with cerebral mucormycosis.' We have shown in previously reported experiments that inoculation o...

245 Opportunistic infections have a high incidence among hematopoetic and solid organ transplant recipients with compromised cell‐mediated immunity induced by immunosuppression.[1] Cytomegalovirus (CMV) infection is frequently seen in the renal transplant recipients, especially those who have received T‐cell depleting antibodies.[2] CMV infection produces immuno‐modulatory effects, resulting in...

BACKGROUND/AIM Mucormycosis is a rare invasive fungal infection most commonly encountered in the immunocompromised host. We analyzed 51 adult patients treated for mucormycosis between 2003 and 2013 and recorded at a tertiary university hospital in Turkey. MATERIALS AND METHODS We examined the following data for all patients: age, sex, predisposing disease, symptoms, treatment, surgical proced...

Mucormycosis is increasingly encountered in immunosuppressed patients, such as those with haematological malignancies or stem cell transplantation. We present a descriptive analysis of 121 cases of mucormycosis from the Prospective Antifungal Therapy Alliance(®) registry (July 2004 to December 2008). Patients with proven or probable mucormycosis were enrolled and followed prospectively for 12 w...

This report presents two cases of invasive rhino-orbital mucormycosis who had life-threatening reactions to amphotericin B. Both cases were treated with a combination of posaconazole-caspofungin favorably with no evidence of recurrence upon long-term follow-up. To our knowledge, this is the first report of successful treatment of invasive mucormycosis with azole-echinocandin combination. It may...

Mucormycosis is a severe fungal infection that largely affects immunocompromised individuals. It carries a high morbidity and mortality rate and is characterised by extensive angioinvasion and necrosis of host tissue. This case report details success in treating disseminated mucormycosis in a paediatric patient with an underlying haematological malignancy. Treatment included institution of comb...

Mucormycosis is an uncommon, but important opportunistic fungal infection. The most commonly reported areas of infection are pulmonary, rhinocerebral and cutaneous. It has only rarely been reported to cause peripheral neurological symptoms. This report presents the case of a patient who presented with ascending paralysis due to pulmonary mucormycosis. The presentation is believed to be due to a...

this study represents an unusual case of mucormycosis localized in nasal cavity of a german shepherd dog. the patient was a 1-year-old male guard dog with unilateral nasal epistaxis, mucopurulent nasal discharge, sneezing and nose pawing. the dog had a history of head trauma about 2 months before admission, which was associated with mild self-limited epistaxis. initial nasal rhinoscopy showed s...

Mucormycosis is a fulminant fungal infection that occurs most often in diabetic and immunocompromised individuals. Our patient, with uncontrolled diabetes mellitus and multiple systemic disorders, developed postextraction mucormycosis of mandible, an extremely rare complication. An initial clinical and radiographic diagnosis of mandibular osteomyelitis was made and the lesion was treated medica...