The discrimination between functionally neutral amino acid substitutions and non-neutral mutations, affecting protein function, is very important for our understanding of diseases. The rapidly growing amounts of experimental data enable the development of computational tools to facilitate the annotation of these substitutions. Here, we describe a Random Forests-based classifier, named Mutation ...

OBJECTIVE To compare results obtained with the NC-stat--an automated nerve testing device--to traditional nerve conduction studies relevant to carpal tunnel syndrome screening. METHODS Thirty-three subjects recruited from patients referred for electrodiagnostic testing were studied. Measurements including the distal motor latency (DML), distal sensory latency (DSL), and median-ulnar latency d...

paraschistura prokofiev, 2009 is a newly described genus based on osteological characters, but detailed information for all species of the genus is not available. to describe osteological characteristics of the endemic species of paraschistura nielseni , twelve specimens were collected from the shapur river of persis basin which drains to the persian gulf and their osteological characteristics ...

cobitis avicennae is a new described species from iranian part of the tigris basin and little information is available on its different aspects of its biology and holomorphology. hence, this study was conducted to provide a detailed description of its osteological features. for this purpose, the specimens of c. avicennae were cleared and stained and a detailed description of its skeletal struct...

in present investigation the biological leaching of aluminum by isolated fungi from red mud, the main waste product of the alkaline extraction of al from bauxite was studied. biological leaching experiments were carried out using indigenous, date and orange specimen fungi, aspergillus niger, penicillium simplicissimum notatum. savored dextrose chloramphenicol agar (sda) was used as medium for t...

MUD (Multiple User Dungeon) systems are client-server. When the single server goes down, everyone is kicked off and no one can log on. Also, even if there are only a handful of people talking in a given room, a large overall number of users can slow the server and cause lag (higher latency) which makes fluent communication impossible. We introduce Happy Fun MUD, a distributed, peer-to-peer MUD ...

During the petroleum well drilling operation many mechanical and hydraulic parameters are observed by an instrumentation system installed in the rig named mud-logging system. The mud-logging system is composed by several sensors distributed in the rig; these sensors measure different operation parameters like: hook load, column rotation, mud pit level, pumping pressure, etc. The mudlogging syst...

Mudboils are round to elongate, 1-3 m diameter bare soil patches that form on perennially frozen till. marine clayey silt, colluvium. or other poorly sorted sediments (muds) with significant silt and (or) clay content. In Keewatin these muds have low liquid limirs (<ZM) and limited plasticity indices (<It)%). Natural moisture contents are very near the liquid limit .w thal rhe muds liquefv and ...

The South American coast between Brazil and Venezuela is affected by longshore migrating mud banks derived from the fine-grained Amazon sediment discharge. Onshore mud migration prevails over shallow ‘bank’ areas alternating alongshore with deeper ‘inter-bank’ areas. The transport on the inner shelf, and attachment to the shoreline, of this migrating mud has been attributed mainly to wind waves...