Drug smuggling is probably the transnational crime generating the greatest revenues to participants, approximately $20 billion, mostly from cocaine and heroin. Migration and other economic factors, together with enforcement, affect all dimensions of the industry; which countries produce and transship; the means by which the drugs are moved; the organizational forms that survive in the market; a...

Abstract In this article, we study robust transshipment under consistent flow constraints. We consider demand uncertainty represented by a finite set of scenarios and characterize subset arcs as so‐called fixed arcs. each scenario, require an integral that satisfies the respective balance addition, on arc, equal for all scenarios. The objective is to minimize maximum cost occurring among show p...

BACKGROUND Computer-based patient simulations (CBPS) are common, effective, instructional methods for medical students, but have limitations. The goal of this project was to describe the development of a CBPS designed to overcome some of these limitations and to perform an online evaluation. METHODS In 1996, patients and families experiencing a common pediatric problem were interviewed, photo...

In pickup and delivery problems vehicles have to transport loads from origins to destinations without transshipment at intermediate locations In this paper we discuss several characteristics that distinguish them from standard vehicle routing problems and present a survey of the problem types and solution methods found in

In pickup and delivery problems vehicles have to transport loads from origins to destinations without transshipment at intermediate locations. In this paper, we describe an algorithm to solve such problems. The algorithm is based on a set partitioning formulation of the problem and uses new column generation and branching schemes.

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