OBJECTIVES To report outcomes of multimodality therapy incorporating surgical resection and intraoperative electron radiotherapy (IOERT) for patients with locoregionally (LR) recurrent or advanced primary urothelial carcinoma. METHODS From 1983 to 2009, 17 patients, consisting of 11 with LR recurrence after cystectomy for bladder carcinoma, 4 with LR recurrence after nephroureterectomy for ur...

In a popular sense, Jehovah's Witnesses (JW) have their creeds, one of which is refusal of blood transfusion. Such refusal may impinge on their proper management, especially in critical situations. We present a case of successful bloodless multimodality therapy, which was performed for a JW. The patient was a 49-year-old woman and JW who had general weakness 7 days before admission. She was dia...

Carcinoma of the esophagus and gastroesophageal junction tumors presenting with locoregional disease are potentially curable, although the cure rate is modest. Many different treatment approaches have been studied, with a multimodality approach associated with a 10% to 15% greater survival advantage compared with a single-modality approach. A systematic review was conducted to address 3 clinica...

The goal of this study is to capture the quantitative optical features of degenerative finger joints based on x-ray aided three-dimensional (3D) diffuse optical tomography (DOT). It is anticipated that the fused imaging technique can be applied to identifying the significant differences between osteoarthritis (OA) and psoriatic arthritis (PA). For a case study, total 6 subjects were selected to...

Alzheimer's disease (AD), is difficult to diagnose due to the subtlety of cognitive impairment. Recent emergence of reliable network characterization techniques based on diffusion tensor imaging (DTI) and resting-state functional magnetic resonance imaging (rs-fMRI) has made the understanding of neurological disorders at a whole-brain connectivity level possible, providing new avenues for brain...

Malignant pleural mesothelioma (MPM) is an asbestos-related disease with a dismal prognosis. Ethic, social, legal and economic parameters are implicated in its management. It is quite clear that multimodality therapy is necessary to improve long-term results but precise treatment schemes have not yet been equivocally accepted. The extent of surgery is questioned and radical operations are highl...

BACKGROUND Retromolar trigone tumors are rare and aggressive malignancies. There is lack of quality evidence pertaining to their management due to the heterogeneity in treatment policies adopted. We retrospectively reviewed the patients of locally advanced retromolar trigone tumors treated with a standard and uniform multimodality management. METHODS A retrospective review of patients with lo...

Despite the use of aggressive single or multimodality treatment protocols, patients with advanced cervical metastases, N2 and N3, have a poor prognosis because of their high risk of regional and distal failure. Moreover, N3 class does not allow resectability and curability to be defined. Numerous trials have been carried out in order to improve the oncological outcomes of patients with advanced...

PURPOSE Validating deformable multimodality image registrations is challenging due to intrinsic differences in signal characteristics and their spatial intensity distributions. Evaluating multimodality registrations using these spatial intensity distributions is also complicated by the fact that these metrics are often employed in the registration optimization process. This work evaluates rigid...

Left-ventricular non-compaction is a myocardial disease of the left ventricle, characterized by exces¬sive trabeculations. The diagnosis relies based on echocardiography and cardiac magnetic resonance imaging. We report case 23-years-old patient diagnosed for ventricular non compaction revealed sinus node dysfunction. This underlines importance using multimodality imaging approach to enable qui...