Organ fibrosis is a pathological condition associated with chronic inflammatory diseases. In fibrosis, excessive deposition of extracellular matrix (ECM) severely impairs tissue architecture and function, eventually resulting in organ failure. This process is mediated primarily by the induction of myofibroblasts, which produce large amounts of collagen I, the main component of the ECM. Accordin...

in many applications the quality of a process or product is best characterized and summarized by a functional relationship between a response variable and one or more explanatory variables. profile monitoring is used to understand and to check the stability of this relationship over time. therefore checking the capability of a profile seems essential. process capability indices have become very...

This paper considers large-scale multistage stochastic linear programs. Sampling is incorporated into the nested decomposition algorithm in a manner which proves to be significantly more efficient than a previous approach. The main advantage of the method arises from maintaining a restricted set of solutions that substantially reduces computation time in each stage of the procedure. Dedicated t...

Anticoagulants are recommended for the prevention and treatment of venous thromboembolism (VTE), prevention of stroke in patients with atrial fibrillation (AF) and secondary prevention in patients with acute coronary syndrome (ACS). There is a clinical need for novel anticoagulants offering improvements over current standard of care, such as fixed oral dosing and no need for routine monitoring....

With rapid development of advanced sensing technologies, rich and complex real-time profile data are available in many industrial processes such as steelforming manufacturing, chemical manufacturing, semiconductor manufacturing. These profile data provide valuable information about the quality or reliability performance of the process or product, and it is often desirable to utilize them to dev...

Hydrologic alternation of river systems is an essential factor human activity. Cascade-dammed waters are characterized by the disturbed outflow material from catchment. Changes in sediment, dissolved load and nutrient balance among base indicators water resource monitoring. This research was based on use hydrological quality data (1984–2017) Indicators Alteration (IHA) method to determine influ...

Monitoring multivariate quality characteristics is very common in production and service environment. Therefore, many control charts have been suggested by authors for monitoring multivariate processes. In another side, profile monitoring is a new approach in the area of statistical process control. In this approach, the quality of a product or a process is characterized by a relation between o...

Abstract. For a system of distributed processes, correctness can be ensured by statically checking whether their composition satisfies the properties of interest. However, web services are distributed processes that dynamically discover properties of other web services. Since the overall system may not be available statically and since each business process is supposed to be relatively simple, ...

It is shown that for a large collection of almost independent martingales in a suitable framework, the martingale property is preserved on the empirical processes almost surely. Under the assumptions of almost independence and essentially identical finite dimensional distributions, it is proven that a large collection of stochastic processes are martingales essentially if and only if so are the...