Background Myocardial first-pass perfusion imaging is a promising diagnostic tool for the assessment of ischemic heart disease. Spiral imaging, due to its high acquisition speed and robustness against motion artifacts, has been successfully combined with the saturation recovery (SR) GRE sequence using a traditional spiral-out trajectory. However, a SR SSFP sequence can provide higher SNR and us...

introduction: this study evaluated the diagnostic value of the dipyridamole induced electrocardiuogram (ecg) cahnges, comparing with myocardial perfusion imaging. materials and methods: 222 patinets were studied with dipyridamole infusion (based on ecg criteria) as well as dipyridamole-myocardial perfusion imaging (mpi). results: abnormal dipyridamole test and abnormal mpi were noted in 11% and...

UNLABELLED Myocardial SPECT may be useful for assessment of the therapeutic effects and the mechanisms of cardiac regeneration medicine. We aimed to assess first the feasibility and the short-term safety of autologous bone marrow-derived mononuclear cell transplantation (BMCT) into the ischemic myocardium in patients who undergo off-pump coronary artery bypass surgery (OPCAB). In addition, we a...

BACKGROUND Current teaching suggests increased perfusion in free transverse rectus abdominis myocutaneous (TRAM) flaps over pedicled TRAM flaps, broadening indications for its use in high risk patients. This study compared perfusion analysis of free muscle-sparing versus pedicle TRAM flaps in vivo in the peri-operative and late post-operative periods. METHODS The SPY-Elite system using...

Introduction: This study evaluated the diagnostic value of the dipyridamole induced electrocardiuogram (ECG) cahnges, comparing with myocardial perfusion imaging. Materials and Methods: 222 patinets were studied with dipyridamole infusion (based on ECG criteria) as well as Dipyridamole-myocardial perfusion imaging (MPI). Results: Abnormal dipyridamole test and abnormal MPI were noted in 1...

In the past decade, significant advances have been made in the ability to image the heart with radionuclide tracers under stress and resting conditions in patients with suspected or known coronary artery disease (CAD) for the detection of ischemia, determination of prognosis, assessment of myocardial viability, preoperative risk assessment for patients undergoing noncardiac surgery, and evaluat...

OBJECTIVE To compare the diagnostic performance of a new dedicated ultrafast solid-state cardiac camera (Discovery NM 530c [DNM]) with standard dual detector cameras (S-SPECT) in myocardial perfusion imaging. The primary goal was a per-patient analysis of diagnostic performance of the DNM using S-SPECT as the reference standard. METHODS AND RESULTS In total, 168 patients underwent one-day Tc-...

OBJECTIVES The aim of this study was to establish a new, dynamic 3-dimensional cardiac magnetic resonance (3D-CMR) perfusion scan technique exploiting data correlation in k-space and time with sensitivity-encoding and to determine its value for the detection of coronary artery disease (CAD) and volumetry of myocardial hypoenhancement (VOLUME(hypo)) before and after percutaneous coronary stentin...

BACKGROUND Experimental data demonstrate the persistence of a transmural vasodilator reserve in the face of depressed resting myocardial perfusion. The present study was designed to determine whether resting myocardial hypoperfusion indicates exhausted coronary reserve (CR). METHODS AND RESULTS Fifteen patients with stable angina, isolated left anterior descending coronary artery (LAD) stenos...

PURPOSE To develop and evaluate an image reconstruction technique for cardiac MRI (CMR) perfusion that uses localized spatio-temporal constraints. METHODS CMR perfusion plays an important role in detecting myocardial ischemia in patients with coronary artery disease. Breath-hold k-t-based image acceleration techniques are typically used in CMR perfusion for superior spatial/temporal resolutio...