Recent studies have demonstrated that T-helper 17 lymphocytes (Th17), which produce mostly IL-17, play a major role in several autoimmune diseases commonly thought to be Th1-related, including Hashimoto's thyroiditis (HT). IL-23, a member of the IL-12 cytokine family, is known to guide T cells toward the Th17 phenotype and its serum levels are increased in several autoimmune disease. Few data a...

Bu çalışmanın amacı Türkiye profesyonel futbol liglerindeki takımların stadyum çim türlerinin ve bu ligler arasındaki dağılımının incelenmesidir. Çalışmada 2020-2021 sezonunda liglerinde yer alan 145 takımın stadyumlarındaki tipleri araştırılmıştır. Stadyum tipi ile ilgili bilgilere Futbol Federasyonu resmi sitesinden yararlanılarak ulaşılmıştır. Eksik bilgiler, kulüplerin web ya da kulüplerle ...

OBJECTIVE To explore the treatment effects of HydroCoil Embolic System (HES) on large- and medium-sized intracranial aneurysms. METHODOLOGY Fifty cases of intracranial aneurysm patients were retrospectively analyzed, in which 27 and 23 cases were treated with HES (n=27) and ordinary coils (n=23), respectively. All the patients were followed up for two years. RESULTS The 27 cases (54%, 27/50...

BACKGROUND In patients undergoing maintenance hemodialysis (HD), increased levels of circulating fibroblast growth factor-23 (FGF-23) are independently associated with cardiovascular events and mortality. Interventional strategies aiming to reduce levels of FGF-23 in HD patients are of particular interest. The purpose of the current study was to compare the impact of high-flux versus low-flux H...

The hereditary hearing-vision loss disease Usher syndrome (USH) is caused by defects in several proteins, most of which form an integrated protein network called Usher interactome. Harmonin/Ush1C is a master scaffold in the assembly of the Usher protein complexes, because harmonin is known to bind to every protein in the Usher interactome. However, the biochemical and structural mechanism gover...

In the title compound, [Zn(2)(C(36)H(42)N(4)O(2))(CH(3)COO)(2)]·2CH(3)CH(2)OH, a centrosymmetric dinuclear zinc macrocyclic complex is accompanied by two half-occupied ethanol solvent molecues resulting in a 1:2 macrocycle-solvent composition. The Zn(II) atom has a square-pyramidal geometry arising from an N(2)O(3) donor set, being coordinated by two N atoms and two O atoms from the macrocyclic...