Based on imaging and spectroscopy obtained at the ESO NTT telescope and using an efficient image analysis algorithm, we study the core of the LMC OB association LH 13, particularly the two compact stellar clusters Sk–66◦41 and HNT in the H ii region N 11C. We resolve Sk–66◦41 into 15 components and for the first time the HNT cluster into 70 stars, and derive photometry for the members. Moreover...

Background: Manual muscle testing (MMT) and Functional index 2(FI-2) are the usual methods in assessing disease activity IIM 1 . Limitations of MMT8 include low sensitivity to change, floor/ceiling effect, under-representation certain important groups while FI-2 takes a longer time administer. Several Timed function tests (TFTs) like 2-minute walk test (2MWT) or 30s raise from chair 1kg arm ris...

YUKO YAMBE,1 YASUKO WATANABE-TOMITA,1 SATOSHI KAKIYA,1 HISASHI YOKOI,1 HIROSHI NAGASAKI,1 HIROSHI ARIMA,1 TAKASHI MURASE,1 HIROMITSU YUASA,1,2 KUNIKAZU KONDO,1,3 HIROSHI YAMASHITA,4 AND YUTAKA OISO1 1First Department of Internal Medicine, Nagoya University School of Medicine, Nagoya 466–8550; 2Nagoya Higashi Municipal Hospital, Nagoya 464–0071; 3Anjo Kosei Hospital, Anjo 446–8602; and 4First De...

König, Jörg, Yunhai Cui, Anne T. Nies, and Dietrich Keppler. A novel human organic anion transporting polypeptide localized to the basolateral hepatocyte membrane. Am. J. Physiol. Gastrointest. Liver Physiol. 278: G156–G164, 2000.—We cloned and expressed a new organic anion transporting polypeptide (OATP), termed human OATP2, (OATP-C, LST-1; symbol SLC21A6), involved in the uptake of various li...

Simaan, May, Serge Picard, Jean St-Louis and Michèle Brochu. Functional alteration of dihydropyridinesensitive Ca21 channels in the adrenal glomerulosa of pregnant rats. Am J Physiol Endocrinol Metab 278: E925–E932, 2000.—Our previous work on aldosterone secretion suggested that dihydropyridine-sensitive calcium channels, one type of voltage-dependent calcium channels (VDCC), are functionally i...

Pausawasdi, N., S. Ramamoorthy, V. Stepan, J. Del Valle, and A. Todisco. Regulation and function of p38 protein kinase in isolated canine gastric parietal cells. Am. J. Physiol. Gastrointest. Liver Physiol. 278: G24–G31, 2000.—We examined the regulation and functional role of p38 kinase in gastric acid secretion. p38 kinase was immunoprecipitated from cell lysates of highly purified gastric par...

Hilton, L. K., and A. B. Loucks. Low energy availability, not exercise stress, suppresses the diurnal rhythm of leptin in healthy young women. Am. J. Physiol. Endocrinol. Metab. 278: E43–E49, 2000.—Because the effect of exercise on leptin was not established, we controlled energy intake (I) and exercise energy expenditure (E) to distinguish the independent effects of energy availability (A 5 I ...

Kuemmerle, John F. Endogenous IGF-I regulates IGF binding protein production in human intestinal smooth muscle cells. Am J Physiol Gastrointest Liver Physiol 278: G710– G717, 2000.—Human intestinal smooth muscle in culture produces insulin-like growth factor (IGF)-I and IGF binding protein (IGFBP)-3, IGFBP-4, and IGFBP-5, which modulate the effects of IGF-I. This study examined the regulation o...

STEPHEN M. WIENER,1 ROBERT F. HOYT, JR.,2 JOHN R. DELEONARDIS,2 RANDALL R. CLEVENGER,2 KENNETH R. JEFFRIES,2 KUNIO NAGASHIMA,3 MYRNA MANDEL,4 JENNIE OWENS,5 MICHAEL ECKHAUS,5 ROBERT J. LUTZ,6 AND BRIAN SAFER1 1Molecular Hematology Branch and 2Laboratory of Animal Medicine and Surgery, National Heart, Lung, and Blood Institute, National Institutes of Health, Bethesda 20892; 3Laboratory of Cell a...

NICOLA L. JONES,1,2,3 AVINASH ISLUR,1 RIZWAN HAQ,4 MARIOLA MASCARENHAS,1 MOHAMED A. KARMALI,2 MARY H. PERDUE,5 BRENT W. ZANKE,4 AND PHILIP M. SHERMAN1,2,3 1Research Institute, Hospital for Sick Children, and Departments of 2Molecular Microbiology and Medical Genetics and 3Pediatrics, University of Toronto, Toronto M5G 1X8; 4Department of Medicine, University of Toronto, Princess Margaret Hospit...