Six years ago a patient suffered a severe allergic reaction from sensitization to methyl methacrylate in a mixture of materials designed to make artificial nails. There was marked erythema, edema, and pain of the eponychial and paronychial tissues with persistent paresthesia of the finger tips. Gradual destruction of the nail plates developed and since no regrowth of the nails resumed in six ye...

Lower extremity ischemia is an important source of morbidity with femoral venoarterial extracorporeal membrane oxygenation support. We describe our experience with the use of a side-arm graft sewn to the femoral artery that facilitates adequate extracorporeal membrane oxygenation flow while preventing lower extremity ischemia.

BACKGROUND The role of ischemia reperfusion contributing to functional impairment in lower extremity peripheral arterial disease (PAD) patients has not previously been elucidated. The evaluation of gait variability patterns has proven useful in many pathologic populations. Therefore, the purpose of this study is to isolate and determine the specific effect of the acute reperfusion phase of isch...

Psoriasis is a chronic inflammatory disease affecting up to 3% of the general population. The prevalence of nail involvement in psoriasis patients varies between 15% and 79%. While the nails represent a small portion of the body surface area, psoriasis in these areas can have a disproportionate influence on a patient's physical and psychosocial activities. Differential diagnosis between an onyc...

The nail-patella syndrome involves a clinical tetrad of changes in the nails, knees, elbows and the presence of iliac horns. Nail changes are the most constant feature: absent, hypoplastic, or dystrophic. A pathognomonic finding is the presence of the triangular lunula. The diagnosis of nail-patella syndrome is based on clinical findings. In this paper we will discuss a case report of this synd...

Onychodystrophy represents various pathologic processes of the nails such as infectious and noninfectious disorders including onychomycosis, psoriasis and allergic and irritant dermatitis. Nail changes may also be a clue to other dermatological or systemic diseases. But often it is difficult to establish the diagnosis as most nail changes are unspecific. The purpose of this article is to give a...

Background: Osteogenesis imperfecta (OI) is a genetic disorder characterized by increased bone fragility and multiple fractures. Approximately 90% are caused mutation in COL1A1 or COL1A2 genes, the disease transmitted either autosomal dominantly recessively appears as spontaneous mutation. Protein product of these two genes type I collagen, major structural protein skin, which affected quality,...

❚ Splinter hemorrhages If you said onycholysis (left) and red lunula (right), you are correct. As for the underlying diseases: The patient with onycholysis has hyperthyroidism and the patient with red lunula has chronic obstructive pulmonary disease (COPD). Onycholysis and red lunula are among the more common changes to the morphology (shape) and color of the nail—the 2 ways by which nail chang...