Fine scale heterogeneities in strontium isotope ratios, 40Ar-39Ar ages, and chemical com~sition have been determined for individual mineral grains and enclaves in the rhyolites of San Vincenzo, Italy. The rhyolites are peraluminous with phenocrysts of alkali feldspar, piagioclase, biotite, and cordierite and have previously been divided into two groups on the basis of whole rock major element c...

Introduction: Individual grains and small lithic clasts in thin-sectioned suevitic breccia samples from the International Continental Scientific Drilling Program (ICDP) Bosumtwi impact crater drillcore LB07A were examined petrographically to evaluate the occurrence , abundance, and characteristics of unshocked and shock-metamorphosed quartz. The analyzed samples were taken across a ~42-m-long (...

A provenance study was conducted on the Mid-Proterozoic Newland Formation, in which petrographical features of sandstones and geochemical characteristics of shales were integrated to arrive at an internally consistent interpretation. Sandstones of the Newland Formation are typically arkosic sands and arkoses with very well rounded quartz and feldspar grains and only minor amounts of extrabasina...

Pharmacological treatment of atrial fibrillation (AF) exhibits limited efficacy. Further developments require a comprehensive characterization of ionic modulators of electrophysiology in human atria. Our aim is to systematically investigate the relative importance of ionic properties in modulating excitability, refractoriness, and rotor dynamics in human atria before and after AF-related electr...

Antismoking mass media campaigns are known to be effective as part of comprehensive tobacco control programs in high-income countries, but such campaigns are relatively new in low- and middle-income countries and there is a need for strong evaluation studies from these regions. This study examines Malaysia's first national antismoking campaign, TAK NAK. The data are from the International Tobac...

Sodium overload of cardiac cells can accompany various pathologies and induce fatal cardiac arrhythmias. We investigate effects of elevated intracellular sodium on the cardiac action potential (AP) and on intracellular calcium using the Luo-Rudy model of a mammalian ventricular myocyte. The results are: 1) During rapid pacing, AP duration (APD) shortens in two phases, a rapid phase without Na(+...

Nur77 is a member of the steroid receptor superfamily and is known to be expressed in animals under stress. We studied the role of nur77 in the regulation of the hypothalamic-pituitary-adrenal (HPA) axis during the stress response using a murine pituitary corticotrope cell line, AtT-20. Corticotropin-releasing hormone (CRH), a stress mediator in the HPA axis, induced the expression of nur77 tra...