Abstract Aim Gentamicin is recommended by local guidelines for the empirical treatment of intra-abdominal sepsis. However, severe side effects that can occur through prolonged raised trough levels requires its use a specific dosing protocol. Challenges this means it often “falls off” drug chart, leading to suboptimal drug-levels. The aim quality improvement project was improve process gentamici...

BACKGROUND Worldwide, cancer of stomach is still the fourth common cancer and the second cause of mortality among all cancers affecting annually 870,000 subjects. This study aims to determine the frequency and the characteristics of gastric cancer in southern Iran. MATERIALS AND METHODS 10,800 of all cancers registered in Fars Hospital-based Cancer Registry were surveyed among which 574 cases...

The 5' untranslated region of hepatitis C virus (HCV) genomic RNA contains an internal ribosome entry site (IRES) element, composed of domains II-IV, which is required for cap-independent translation initiation. Little information on the 3D structure of the whole functional HCV IRES is still available. Here, we use atomic force microscopy to visualize the HCV IRES conformation in its natural se...

BACKGROUND Somatic cell selection in plants allows the recovery of spontaneous mutants from cell cultures. When coupled with the regeneration of plants it allows an effective approach for the recovery of novel traits in plants. This study undertook somatic cell selection in the potato (Solanum tuberosum L.) cultivar 'Iwa' using the sulfonylurea herbicide, chlorsulfuron, as a positive selection ...

Deadline: Friday, December 12, 2014 Please visit www.asnr.org/2015 for more information April 25-30, 2015 Sheraton Chicago Hotel & Towers Request Programming and Registration Materials for the ASNR 53rd Annual Meeting, Contact: ASNR 53rd Annual Meeting c/o American Society of Neuroradiology 800 Enterprise Drive, Suite 205 Oak Brook, Illinois 60523-4216 Phone: 630-574-0220 Fax: 630-574-0661 Emai...

BACKGROUND A large number of human tumor-associated antigens that are recognized by CD8(+) T cells in a human leukocyte antigen class I (HLA-I)-restricted fashion have been identified. Special AT-rich sequence binding protein 1 (SATB1) is highly expressed in many types of human cancers as part of their neoplastic phenotype, and up-regulation of SATB1 expression is essential for tumor survival a...