The effect of anaerobic physical training and nandrolone treatment on the sensitivity to phenylephrine in thoracic aorta and lipoprotein plasma levels of rats was studied. Sedentary and trained male Wistar rats were treated with vehicle or nandrolone (5 mg/kg IM; twice per week) for 6 weeks. Training was performed by jumping into water (4 sets, 10 repetitions, 30-second rest, 50% to 70% body we...

The relationship of strength to muscle area was used to assess change in muscle quality after anabolic interventions. Study 1: asymptomatic human immunodeficiency virus-positive men (39 +/- 9 yr) were randomized to nandrolone (600 mg/wk) +/- resistance training (RT). Study 2: older healthy men (72 +/- 5 yr) were randomized to oxandrolone (20 mg/day) or placebo. Maximum voluntary strength was de...

BACKGROUND We analyzed data retrieved through a PubMed search of randomized, placebo-controlled trials of first-generation antipsychotic long-acting injectables (haloperidol decanoate, bromperidol decanoate, and fluphenazine decanoate), and a company database of paliperidone palmitate, to compare the benefit-risk ratio in patients with schizophrenia. METHODS From the eight studies that met ou...

In this study, the effect of mixing a small amount ammonia on ignition delay time methyl decanoate under different conditions was studied from perspective combustion mechanism. The adding at pressures and temperatures by means simulation calculations numerical comparison. Integrating detailed mechanism reaction path decanoate, sensitivity investigated. Analyses rate production were conducted to...

The metabolism of the tumor promoters 120-O-[3H]tetradecanoylphorbol-13-acetate ([3H]TPA) and [3H]phorbol-12,13-didecanoate ([3H]PDD) was analyzed in several cell types in culture. In contrast to the rapid metabolism of [3H]TPA, [3H]PDD was degraded much more slowly in hamster, rat, chick, and mouse fibroblasts. Human fibroblasts did not significantly metabolize either phorbol diester over a th...

Nandrolone or 19-nortestosterone, or 17ß-hydroxy-19-nor-4-androsten-3-one, has been one of the most abused anabolic steroids and doping practices are increasing, as revealed by numerous positive cases during the last 5 years in various sports. The drug accelerates muscle growth by an anabolic effect. Athletes use nandrolone because it has been claimed that it increases lean body mass, increases...

Characterized by low serum testosterone levels and diverse symptoms, male hypogonadism is a common condition. Current medical treatment focuses on testosterone supplementation using multiple modalities such as injections, gels and pellets. Interestingly, while testosterone is considered an anabolic androgenic steroid, it has not been saddled with the social stigma that other, similar medication...

background: nandrolone decanoate (nd) is an anabolic androgenic steroid (aas) which influences the ovarian structure and function. we assessed the effects of nd on the ovarian volume, number of primordial follicles, and level of hormones and also evaluated the modulatory effects of gonadotropins on the histopathological changes imposed by the administration of nd. methods: six groups of sprague...