charges and extrinsically trapped charges in biomolecules by use of a nanogap embedded biotransistor Sungho Kim, Jae-Hyuk Ahn, Tae Jung Park, Sang Yup Lee, and Yang-Kyu Choi School of Electrical Engineering and Computer Science, Division of Electrical Engineering, KAIST, Daejeon 305-701, Republic of Korea BioProcess Engineering Research Center, Center for Systems and Synthetic Biotechnology, an...

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Wavelet transformation was applied as an elimination method of influence by an interfering substance on an amperometric biosensor. The current responses of a bi-enzyme type lactose biosensor in a solution containing both lactose and ascorbic acid were analyzed by wavelet transformation. The power spectrum density for ascorbic acid was detected selectively at around 0.125 Hz. The current compone...

BACKGROUND Glucose-6-phosphate-dehydrogenase-deficiency (G6PDd) is a major risk factor for primaquine-induced haemolysis. There is a need for improved point-of-care and laboratory-based G6PD diagnostics to unsure safe use of primaquine. METHODS G6PD activities of participants in a cross-sectional survey in Bangladesh were assessed using two novel quantitative assays, the modified WST-8 test a...

We demonstrate a powerful SERS-nanoreactor concept composed of self-assembled gold nanoparticles (AuNP) linked by the sub-nm macrocycle cucurbit[n]uril (CB[n]). The CB[n] functions simultaneously as a nanoscale reaction vessel, sequestering and templating a photoreaction within, and also as a powerful SERS-transducer through the large field enhancements generated within the nanojunctions that C...

This work reports a versatile platform for manipulation and sensing of biological molecules based on electrode nanogaps, which function as dielectrophoresis-enabled molecular trapping templates as well as spectroscopic and nanoelectronic detection substrates. On a chip, an array was constructed of Ti/Al nanoelectrode pairs with gap dimensions ranging from few tens of nm to <10 nm. During the mo...